Aloe Emodin hmoov

Xi'an Kintai Biotech Inc yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm aloe emodin hmoov hauv Suav teb. Thov koj xav tias dawb rau cov lag luam wholesale zoo aloe emodin hmoov muag ntawm no los ntawm peb lub hoobkas. Rau nqe kev sab laj, tiv tauj peb.

KINTAIBIO^®'s Aloe Emodin hmoovyog ib qho siab -purity anthraquinone natural active ingredient. Peb tus qauv specification yog 95% aloe-emodin, tshwm raws li txiv kab ntxwv koob-zoo li cov muaju los yog yellowish- xim av crystalline hmoov. Cov khoom yog muab rho tawm los ntawm ntau qhov chaw, feem ntau cov tshuaj ntsuab nroj tsuag xws li aloe, rhubarb, thiab polygonum cuspidatum, tag nrho kom ntseeg tau lub ntuj tsim thiab cov khoom xyaw nquag ntawm cov ntaub ntawv raw.Aloe emodinmuaj keeb kwm ntev ntawm kev siv tshuaj hauv Suav Tshuaj Kho Mob thiab tau txais kev saib xyuas thoob plaws vim nws ntau yam kev ua haujlwm tshuaj.

Nyob rau hauv cov nqe lus ntawm daim ntawv thov, vim nws ntau yam kev ua ub no xws li tshuaj tiv thaiv -inflammatory, antibacterial, antiviral, antitumor, immunosuppressive, neuroprotective, thiab hepatoprotective teebmeem, nws yog dav siv nyob rau hauv kev tsim tshuaj, tshuaj pleev ib ce, thiab functional khoom. Hauv kev lag luam tshuaj pleev ib ce, nws yog siv los ua cov khoom siv cog qoob loo nrog soothing, kho, tiv thaiv hnub ci, thiab tom qab- tiv thaiv tshav ntuj; hauv kev lag luam tshuaj, nws txoj kev tswj lub plab zom mov, tiv thaiv - mob, thiab cov teebmeem neuroprotective muab siab - cov khoom xyaw zoo rau cov tshuaj muaj feem xyuam; nws daim ntawv hmoov kuj yooj yim hloov tau yooj yim formulation thiab yog haum rau ntau yam khoom siv xws li kev tu tawv nqaij thiab plaub hau.

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Hais txog cov khoom zoo, peb95% Aloe Emodin hmoovnta lub hauv paus ntsiab lus ntshiab, purity siab, thiab kev ua haujlwm ruaj khov. Raws li cov kws tshaj lij cog extract chaw tsim khoom, peb nruj me ntsis tswj cov khoom siv raw thiab cov txheej txheem ntau lawm. Yog xav paub ntxiv txog cov khoom, thov hu rau peb ntawmsales@kintaibio.com.

Raw Khoom Pretreatment

Siv rhubarb raw khoom thiab pulverize nws mus rau 20-80 mesh siv lub pulverizer. Nyob rau hauv cov pa ntau lawm, pulverization loj yog tswj nyob ib ncig ntawm 40 mesh kom nce qhov chaw nto ntawm cov khoom thiab txhim kho cov efficiency ntawm tom ntej enzymatic hydrolysis thiab extraction.

Enzymatic Hydrolysis

Ntxiv 1-2 zaug ntawm qhov hnyav ntawm dej (zoo dua 1.2 zaug) rau cov khoom siv pulverized rhubarb rau ntub dej. Tom qab ntawd ntxiv 0.1% -0.5% ntawm cov enzyme compound (zoo dua 0.3% glucosidase) thiab hydrolyze ntawm 30-50℃rau 2-5 teev (zoo dua 3 teev ntawm 40 degree). Cov enzyme uas siv tuaj yeem yog ib qho los yog ua ke ntawm cellulase, glucosidase, rhamnosidase, thiab pectinase.

Organic Solvent Extraction

Tom qab enzymatic hydrolysis, ntxiv 3-10 npaug ntawm qhov hnyav ntawm cov kuab tshuaj organic (zoo dua 6 zaug) rau hydrolysate. Cov kuab tshuaj organic yuav tsum yog 70% -90% methanol aqueous tov los yog ethanol aqueous tov (zoo dua 80% ethanol aqueous tov). Extraction yog nqa tawm ntawm 70-80 degree. Kev rho tawm yog ua 1-3 zaug (zoo dua 3 zaug), thiab cov rho tawm los ntawm txhua qhov kev rho tawm yog ua ke. Tom qab tshem tawm, mloog zoo rau cov extract mus rau ib qho kev nqus ntawm 1.05–1.20, nyiam dua rau 1.15–1.20 (xws li, 1.17).

Alkali-Alcohol Dissolution

Ntxiv 20-50 npaug ntawm nws qhov loj ntawm 80% -90% methanol lossis ethanol aqueous tov (zoo dua 40 npaug ntawm nws qhov loj ntawm 85% ethanol aqueous tov) rau cov extract, thiab ib txhij ntxiv 20% -30% ntawm cov extract qhov loj ntawm cov tshuaj alkaline (xws li sodium 25%). Dissolve ntawm 75-85℃rau 2-5 teev (zoo dua 3 teev ntawm 75 degree). Cov tshuaj alkaline tuaj yeem yog ib qho los yog sib xyaw ntawm sodium hydroxide, potassium hydroxide, sodium carbonate, potassium carbonate, thiab sodium bicarbonate. Tom qab dissolution, lim. Rov ua kom pom ntawm qhov seem thiab sim covaloe -emodincov ntsiab lus kom txog rau thaum aloe- cov ntsiab lus emodin nyob rau hauv qhov seem yog Tsawg dua los yog sib npaug rau 2.0%. Sau thiab ua ke cov filtrates.

Acid Precipitation thiab Purification

Cov filtrates ua ke tau tso cai kom txias rau chav tsev kub, thiab cov kua qaub ntxiv los kho cov pH rau 3-5 (zoo dua pH 3). Cov dej nag tau tso cai tshwm sim rau 0.5-2 teev (zoo dua 0.5 teev). Ib lossis ntau qhov sib xyaw ua ke ntawm sulfuric acid, hydrochloric acid, citric acid, glacial acetic acid, thiab oxalic acid tuaj yeem siv. Tom qab nag lossis daus, cov dej nag yog lim thiab ntxuav nrog dej, cawv, dichloromethane, lossis n-hexane. Thaum kawg, nws yog qhuav kom tau covAloe Emodin hmoovkhoom.

Aloe Emodin Powder For Inflammatory

Cov tshuaj tiv thaiv -inflammatory mechanism ntawmaloe emodin hmoovkoom nrog ntau txoj hauv kev taw qhia tseem ceeb, nthuav tawm ntau- lub hom phiaj thiab ntau- theem kev tswj hwm tus yam ntxwv. Cov kev tshawb fawb tau piav qhia txog kev tiv thaiv kev tiv thaiv - cov txheej txheem inflammatory ntawm aloe emodin siv cov qauv nas ntawm nruab nrab cerebral artery occlusion thiab reperfusion, oxygen-glucose deprivation thiab reperfusion cell qauv, thiab lipopolysaccharide- stimulated cell qauv. Cov txiaj ntsig tau pom tias aloe emodin tuaj yeem hla cov ntshav- lub paj hlwb teeb meem, txo qhov mob ntawm lub paj hlwb thiab txhim kho cov qhab nia ntawm tus cwj pwm. Qhov kev sim no qhia meej meej txog cov txheej txheem molecular uas aloe emodin exertsnws cov tshuaj tiv thaiv -inflammatory thiab neuroprotective los ntawm kev tswj cov PI3K/AKT/mTOR thiab NF-κB txoj kev taw qhia.

 

Lwm qhov kev tshuaj xyuas qhia tau hais tias anthraquinone tebchaw thiab aloe rho tawm tuaj yeem tswj hwm cov tshuaj hormone homeostasis, autoantibody ntau lawm, thiab cytokine/chemokine signaling (xws li IL-1 , TNF- , thiab IFN- ), inhibiting NF-kTP thiab kev tswj hwm ntawm MAKP3. txoj hauv kev, thaum tib lub sijhawm txhim kho cov tshuaj tiv thaiv antioxidant, rov ua kom lub cev tsis muaj zog, thiab hloov kho cov txheej txheem ua kom muaj kab mob sib kis thiab tiv thaiv kev tiv thaiv kab mob. Cov kev tshawb pom no qhia tiascov tshuaj tiv thaiv -inflammatory teebmeem ntawmAloe Emodintsis yog tsuas yog xav txog hauv cov kev cai ntawm cov kab mob inflammatory kab mob, tab sis kuj nyob rau hauv kev cuam tshuam ntawm mob o - tsav cov kab mob autoimmune, kab mob neurodegenerative, thiab hnub nyoog- kab mob ntsig txog.

Aloe Emodin hmoov rau Cancer

Cov kev tshawb fawb yav dhau los tau qhia tiasAloe Emodin hmoovtuaj yeem cuam tshuam kev loj hlob ntawm tib neeg melanoma hlwb thiab cuam tshuam lawv cov metabolic plasticity. Txoj kev tshawb no yog thawj zaug qhia txog cov txheej txheem molecular uas Aloe Emodin cuam tshuam cov metabolic plasticity ntawm melanoma hlwb. Kev tshawb fawb pom tiasAloe Emodintuaj yeem cuam tshuam ob lub zog loj - ua txoj hauv kev: glycolysis thiab oxidative phosphorylation, hauv paus txiav tawm ntawm tes lub zog; Nws kuj ua rau cov piam thaj metabolism tsis zoo, txo cov intermediates hauv lub voj voog tricarboxylic acid, thiab ua rau muaj kev sib txuam loj ntawm cov pa oxygen reactive hauv mitochondria, ua rau oxidative kev nyuaj siab thiab kev tsis sib haum xeeb hauv redox homeostasis.

 

Tau ntsib nrog ntau qhov kev tawm tsam no, cov hlwb melanoma uas muaj cov kab mob metabolic sib txawv sim pib cov lus teb hloov pauv -xws li upregulating antioxidant tiv thaiv mechanisms lossis txhim kho ib qho -carbon metabolism thiab amino acid txoj hauv kev los tswj nucleotide synthesis-tab sis tsis muaj leej twg tuaj yeem tiv thaiv kev cuam tshuam ntawm lawv cov metabolic network los ntawm Al. Qhov tseem ceeb ntawm qhov kev tshawb fawb no nyob hauv qhov tseeb tiasAloe Emodin hmoovtuaj yeem ua tiav lub hom phiaj tsis zoo hauv ntau yam metabolic phenotypes, ua kom pom lub peev xwm zoo los kov yeej cov tshuaj tiv thaiv kab mob thiab ua ntej cov tswv yim kho mob melanoma.

Aloe Emodin Hmoov Rau Antibacterial

PebAloe Emodin hmoovtau pom ib qho kev nthuav dav hauv nws cov kab mob muaj peev xwm los ntawm kev hloov kho cov qauv, nrog nws cov derivatives nthuav tawm ntau yam kev sib koom ua ke ntawm cov tshuaj tua kab mob ntau tshaj li cov tshuaj tua kab mob. Kev kawmtsim thiab tsim ib qho aloe-emodin-sulfonylhydrazone derivative, aloe-emodin-benzenesulfonylhydrazone (AEBH-5a), uas tau ua tiav qhov tsawg kawg nkaus inhibitory concentration (MIC) ntawm 0.5 ug / mL tiv thaiv Staphylococcus aureus 25923, ua kom pom cov kab mob zoo dua qub piv rau cov tshuaj siv tshuaj norfloxacin, thiab pom muaj kev xaiv siab ntawm cov kab mob thiab cov kab mob mammalian cell membranes.

 

Qhov tshwj xeeb zoo ntawm cov tshuaj no yog nyob rau hauv nws cov multi-theem, multi-target antibacterial mechanism. Qhov tseem ceeb tshaj, AEBH-5a tuaj yeem tshem tawm cov biofilms uas twb muaj lawm thiab ncua kev txhim kho cov kab mob tsis zoo. Kev sim hauv computer ntawm ADME txoj kev tshawb fawb kwv yees tias qhov derivative no muaj bioavailability zoo thiab cov khoom zoo li tshuaj. Qhov kev tshawb fawb no qhia tau hais tias kev tsim kho kom zoo raws li cov qauvAloe Emodincore tuaj yeem tso nws nrog ntau yam kev sib koom ua ke los tiv thaiv kab mob, muab lub tswv yim zoo thiab muaj txiaj ntsig rau kev tsim cov tshuaj tua kab mob tshiab tshiab thiab hais txog qhov kev hem thawj loj ntawm cov kab mob.

Siv:https://pubmed.ncbi.nlm.nih.gov/34286782/

https://pubmed.ncbi.nlm.nih.gov/40142026/

https://pubmed.ncbi.nlm.nih.gov/40218871/

https://pubmed.ncbi.nlm.nih.gov/35870413/

aloe emodin ntxiv

Aloe emodintuaj yeem raug formulated rau hauv ntau hom tshuaj xws lialoe emodin ntsiav tshuajthiabaloe emodin ntsiav tshuaj, siv los ua cov khoom noj muaj txiaj ntsig zoo los pab tswj cov hnyuv ua haujlwm, txhim kho lub cev muaj peev xwm antioxidant, thiab ua tau raws li cov neeg siv khoom noj kev noj qab haus huv txhua hnub.

• Hauv kev kho mob, cov khoom no tuaj yeem siv ncaj qha los ua cov khoom muaj zog rau kev tiv thaiv - mob, tiv thaiv - qog, thiab cov kab mob hauv plab hnyuv txhim kho, rau kev kho pob txuv, kab mob ntawm daim tawv nqaij, adjuvant anti- kho mob qog noj ntshav, thiab cem quav, thaum tseem muaj kev tiv thaiv ntawm daim siab thiab lub raum ua haujlwm.
• Hauv kev lag luam khoom noj khoom haus, vim nws cov khoom siv tshuaj tua kab mob ntuj, nws tuaj yeem siv los ua cov khoom noj khoom haus kom ntev lub neej txee, thiab kuj yog cov khoom noj khoom haus ntxiv, muab dej haus thiab cov khoom noj qab haus huv ntxiv rau kev noj qab haus huv.
• Hauv kev lag luam tshuaj lom neeg niaj hnub, nws cov tshuaj tua kab mob antioxidant thiab tiv thaiv - pob txuv inflammatory - txo cov khoom ua rau nws yog ib qho zoo tshaj plaws natural additive nyob rau hauv cov khoom tu tawv nqaij xws li cream, lotions, thiab serums; Thaum ntxiv rau cov tshuaj zawv plaub hau thiab cov tshuaj kho mob, nws tuaj yeem ua rau tawv taub hau, txo cov plaub hau poob thiab dandruff, thiab ua rau cov plaub hau muaj zog thiab ci iab.

Aloe Emodin hmoovmuaj kev nyab xeeb zoo profile thaum siv kom tsim nyog, tab sis tej zaum yuav tsum tau ceev faj txog kev nyab xeeb yuav tsum tau coj mus rau hauv tus account thaum siv.

• Qee tus neeg rhiab heev tej zaum yuav muaj kev tsis haum tshuaj rau cov tshuaj anthraquinone hauv aloe vera, tshwm sim raws li tawv nqaij khaus, liab, o, lossis khaus. Yog li ntawd, cov neeg tsis haum rau aloe vera los yog muaj keeb kwm ntawm kev ua xua yuav tsum tau siv nrog ceev faj lossis tsis txhob sib cuag tag nrho.
• Hais txog kev noj ntau npaum li cas, cov tshuaj pom zoo yuav tsum tau ua raws li nruj me ntsis. Cov koob tshuaj ntau yuav ua rau muaj kev pheej hmoo ntawm kev phiv tshuaj; yog li ntawd, nws raug pom zoo kom ua raws li lub hauv paus ntsiab lus ntawm kev noj tshuaj kom tsim nyog thiab tsis txhob noj ntau dhau lossis siv sijhawm ntev.
• Tsis tas li ntawd, raws li ib tug active ingredient,Aloe Emodintuaj yeem cuam tshuam nrog qee yam tshuaj. Cov tib neeg tam sim no tau txais lwm cov tshuaj yuav tsum sab laj nrog kws kho mob lossis kws muag tshuaj ua ntej siv.
• Txhawm rau kom muaj kev nyab xeeb, nws raug nquahu kom xaiv cov khoom lag luam los ntawm cov tuam txhab muaj npe nrov nrog cov purity siab thiab tswj tau zoo kom tsis txhob muaj kev pheej hmoo los ntawm cov khoom tsis zoo lossis cov khoom tsis zoo.

Zuag qhia tag nrho,Aloe Emodin hmoovmuaj kev nyab xeeb zoo rau cov tib neeg noj qab nyob zoo thaum siv kev tshawb fawb thiab raug. Txawm li cas los xij, cov neeg uas muaj kev fab tshuaj, lub siab tsis zoo lossis lub raum tsis ua haujlwm, lossis tam sim no noj tshuaj raug qhia kom sab laj nrog kws kho mob ua ntej siv.

KINTAIBIO^®tau cog lus los muab cov neeg siv khoom zoo siab - zooAloe Emodin hmoov. Tag nrho cov khoom raug tsim nyob rau hauv ib puag ncig huv si thiab nruj tswj hwm los ntawm cov kws tshaj lij los xyuas kom ua raws li cov qauv thoob ntiaj teb. Lub tuam txhab muaj lub peev xwm los txhim kho kom ruaj khov siab -purity active cov khoom xyaw los ntawm raw cov ntaub ntawv xws li aloe vera, rhubarb, thiab knotweed, thiab tau tsim ib tug zoo meej tswj system, kom ntseeg tau tias txhua batch yog traceable thiab verifiable.

Rau tam sim noaloe emodin nqilos yog nug txogmuas aloe emodin, thov hu rau peb ncaj qha rau cov ncauj lus kom ntxaws thiab cov lus qhia. Peb muab kev sib koom tes yooj yim los ntawm kev sim cov qauv mus rau qhov loj - cov khoom loj, thiab muab tag nrho - cov txheej txheem kev txhawb nqa los ntawm cov ntaub ntawv raw mus rau kev txhim kho daim ntawv thov, pab koj innovate koj cov khoom thiab tso tawm rau hauv kev ua lag luam.Koj tuaj yeem tiv tauj peb ntawmsales@kintaibio.com.

Cim npe nrov: Tuam Tshoj aloe emodin hmoov manufacturers, lwm tus neeg, Hoobkas