Nees txiv ntseejmuaj keeb kwm ntev ntawm kev siv tshuaj hauv tshuaj. Kev tshawb fawb niaj hnub no qhia tias nws cov khoom tseem ceeb yog aescin, triterpenoid saponin compound. Cov khoom no tsis yog tsuas yog ib qho tseem ceeb qhia rau kev ntsuam xyuas qhov zoo ntawm raw cov ntaub ntawv thiab formulations, tab sis kuj cov ntaub ntawv hauv paus rau nws pharmacological efficiency.
Aescinmuaj cov haujlwm zoo -txhais chaw muag tshuaj. Nyob rau hauv lub venous system, nws exerts anti-inflammatory, anti- edema, thiab venous rov- txhawb kev cuam tshuam los ntawm inhibiting serum proteolytic enzymes, stabilizing lysosomal daim nyias nyias, thiab txo capillary permeability. Hauv kev saib xyuas ntawm daim tawv nqaij, aescin tiv thaiv hyaluronic acid los ntawm kev degradation, inhibits collagenase kev ua, pab txo qis kev tsim, txhim kho daim tawv nqaij elasticity, thiab nthuav tawm cov kev ua haujlwm zoo antioxidant. Tsis tas li ntawd, nws muaj txiaj ntsig zoo txhawb microcirculation thiab qhia tau hais tias muaj kev cia siab rau daim ntawv thov kev kho mob rau lub hlwb ua haujlwm rov qab.
Raws li ib tug manufacturers ntawmsiab -purity aescin extract hmoov, KINTAIBIO®siv scientific thiab tswj extraction thiab purification technologies kom tau siab -tus qauv, qis- impurity, thiab bioactively ruaj khovNees Chestnut Extract hmoov khoom. Peb ruaj khov ntseeg tias kev tsim kho thev naus laus zis txuas ntxiv thiab kev tswj cov txheej txheem nruj yog qhov tseem ceeb los ua kom cov khoom zoo thiab ua tau raws li qhov xav tau ntawm cov neeg siv khoom hauv kev lag luam tshuaj, tshuaj pleev ib ce, thiab khoom noj khoom haus.
Ua Nees Chestnut Extract: Raw Khoom Xaiv thiab Kev Npaj
KINTAIBIO®tau tsim kom muaj kev tswj xyuas zoo los ntawm qhov chaw los xyuas kom meej tias txhua pawg ntawm cov noob txiv ntoo cov khoom siv raw khoom ua tau raws li cov qauv kev tswj hwm sab hauv thiab cov kev cai hauv tsev thiab thoob ntiaj teb.
Kev xaiv ntau yam
Peb xaiv siab - zooNees Chestnuts, muab qhov tseem ceeb ntawm kev yuav cov txiv hmab txiv ntoo uas paub tab, plump los ntawm cov chaw tsim khoom tiag tiag lossis cov qauv cog qoob loo. Peb tsuas yog siv cov noob tsis paub tab vim tias cov noob tsis paub tab tsis sau cov aescin txaus, thaum overripe los yog tsis raug khaws cia cov ntaub ntawv raw yuav muaj kev degradation ntawm cov khoom xyaw nquag los yog ua rau tsis zoo.
Kev soj ntsuam zoo
Tag nrho cov khoom siv raw tau raug kuaj nruj thiab kuaj ua ntej warehouses. Txhua batch raug tshuaj xyuas qhov tsos, xim, thiab tsw, thiab cov khoom nyoos uas muaj pwm, kab - kis tau, oily, lossis muaj cov khoom txawv teb chaws raug muab pov tseg. Hnyav hlau txwv nruj nruj raws li EU thiab US cov qauv. Cov tshuaj tua kab residues feem ntau yog saib xyuas rau organochlorine, organophosphorus, thiab tshuaj tua kab pyrethroid. Kev ntsuam xyuas Aflatoxin kom ntseeg tau tias cov khoom siv raw tsis muaj pwm txaus.
Pretreatment Theem
Ua ntej, lub plhaub tawv tawv thiab tsis yog - cov tshuaj raug tshem tawm, thiab cov kernels raug xaiv kom zoo, tom qab ntawd crushed me ntsis. Cov khoom siv crushed muaj ib qho me me me me thiab qhov loj me me ntawm thaj chaw tshwj xeeb, uas ua rau muaj kev sib cuag txaus ntawm cov kuab tshuaj thiab cov khoom xyaw nquag thaum lub sij hawm tom qab rho tawm, yog li txhim kho kev ua haujlwm ntawm extraction.
Ua Nees Chestnut Extract Core Extraction thiab Purification txheej txheem
Ethanol Extraction thiab Degreasing
Thawj kauj ruam hauv cov txheej txheem extraction yog ethanol extraction thiab degreasing. Lub crushednees txiv ntseejmuab tso rau hauv ib lub tank ntau-functional extraction tank, thiab 6 mus rau 10 npaug ntawm cov ether ntxiv rau reflux degreasing. Cov kua degreasing yog muab pov tseg. Tom qab ntawd cov degreased residue tau sau, thiab 8 mus rau 15 npaug ntawm 95% ethanol ntxiv. Lub ultrasonic- pab extraction ntaus ntawv yog qhib, thiab extraction yog ua 2 mus rau 3 zaug ntawm 40 mus rau 75℃thiab ib tug ultrasonic zaus ntawm 40 mus rau 60 kHz. Tom qab kev rho tawm, cov khoom sib cais yog ua tiav los ntawm cov kua centrifuge los yog disc centrifuge, thiab cov ntaub ntawv qhia meej tau sau tseg.
Activated Carbon Decolorization
Pharmaceutical- qib activated carbon, sib npaug li 0.3% rau 0.8% ntawm cov extract ntim, ntxiv rau cov extract. Cov sib tov yog rhuab nyob rau hauv reflux nrog stirring rau 30 mus rau 60 feeb. Cov pa roj carbon activated, nrog nws cov qauv microporous ntau thiab thaj chaw loj tshwj xeeb, tuaj yeem nqus cov xim, colloids, thiab qee cov polar uas tsis yog -saponin impurities hauv cov extract. Cov kauj ruam no yog ib qho tseem ceeb pretreatment kom tau txais lub teeb -xim lossis txawm tias dawb cov khoom kawg.
Membrane Separation thiab Purification
Cov tshuaj decolorized yog thawj microfiltered los ntawm 0.2-micron ceramic membrane module. Ceramic daim nyias nyias muaj qhov zoo ntawm qhov kub thiab txias tsis kam, acid thiab alkali tsis kam, thiab yooj yim tu thiab rov tsim dua tshiab, thiab tuaj yeem khaws cov tshuaj seem seem, colloids, thiab loj molecular suspended solids, ua kom pom tseeb microfiltrate. Lub microfiltrate yog tom qab ntawd dhau los ntawm qhov khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob khoob. Membrane sib cais tshuab ua rau cov molecular-theem fractional purification, zoo tshem tawm cov impurities loj xws li cov proteins thiab polysaccharides, thiab txhim kho cov purity ntawm cov extract.
Macroporous Adsorption Resin Chromatography
Concentrate lub ultrafiltrate rau ib qho cawv concentration ntawm 15% -20% thiab thauj nws mus rau ib tug macroporous adsorption resin kem. Cov hom resin tsim nyog suav nrog NKA-9, NKA-2, X-5, thiab D-4006. Elute sequentially nrog dej huv thiab 60% ethanol, siv 3-5 kem ntim ntawm eluent ntawm tus nqi ntws ntawm 1-4 BV / h. Sau cov 60% ethanol eluent feem nplua nuj nyob rau hauvaescin.
Crystallization thiab Recrystallization
Nco ntsoov sauNees Chestnut Extract feem ntawm 1/5 mus rau 1/15 ntawm nws qhov ntim thawj, tso cai rau nws sawv ntsug, thiab tso cai rau cov muaju los ua kom dej nag. Lim kom tau cov khoom siv lead ua tsis zoo. Ntxuav cov crystals crude nrog ether kom tshem tawm cov organic impurities seem. Dissolve hauv acetone, thiab maj mam ntxiv me me ntawm ether kom induce recrystallization. Cia sawv ntsug, lim, thiab sau cov muaju. Rov ua qhov txheej txheem no 2-3 zaug. Qhov kawg siv lead ua yog lub tshuab nqus tsev qhuav ntawm 60-85℃kom tau txais high-purityAescin Extract hmoov.
Aescin Extract hmoov siv
Hauv kev lag luam raw khoom,Aescinyog siv los ua ib qho tshuaj muaj txiaj ntsig hauv kev tsim cov tshuaj formulations los txhim kho cov tsos mob ntsig txog mob venous insufficiency, xws li txo qis qis o, hnyav, mob, thiab nocturnal cramps; rau kho mob hemorrhoid flare-ups; thiab kho cov nqaij mos o tom qab phais lossis raug mob. Cov ntawv siv tshuaj muaj xws li cov tshuaj hauv qhov ncauj xws li Aescin ntsiav tshuaj thiab Aescin capsules, tshuaj pleev ib ce xws li Aescin gels thiab Aescin cream, thiab txhaj tshuaj.
Nyob rau hauv cov khoom xyaw tshuaj pleev ib ce, Aescin exerts nws cov teebmeem los ntawm ntau yam mechanisms. Nws muaj peev xwm inhibit neutrophil kev ua si thiab tso tawm inflammatory mediators, txo cov tawv nqaij o; nws kuj inhibits collagenase thiab hyaluronidase kev ua, tiv thaiv daim tawv nqaij matrix, txo wrinkle tsim, thiab scavenging dawb radicals kom ncua kev yees duab. Raws li cov teebmeem no, Aescin tau siv dav hauvAescin eye cream, slimming and Aescin firming creams, anti-aging serums, and after-sun repair products.
Hauv cov khoom noj khoom haus thiab kev noj hausAescin ntxivsector, nws yog siv los ua cov khoom noj khoom haus ntxiv los txhawb kev noj qab haus huv ntawm venous, txhim kho ceg tsis xis nyob thiab tswj microvascular kev ncaj ncees. Cov ntaub ntawv muaj xws li cov ntsiav tshuaj, ntsiav tshuaj, tshuaj ntsiav, thiab kua dej haus.
Qhov twg yuav Aescin Extract hmoov?
KINTAIBIO®tsom mus rau kev tshawb fawb thiab kev tsim khoom ntawm high -purity cog extracts. PebNees Chestnut Extract hmoovsiv hwm Aesculus Hippocastanum raw cov ntaub ntawv thiab ib tug advanced ultrasonic- pab extraction-membrane sib cais-macroporous resin-recrystallization txheej txheem, kom muaj kev ruaj ntseg nyob rau hauv cov ntsiab lus, purity, thiab active ingredient profiles rau txhua batch. Peb muab siab - zooAescin Extract hmoovrau cov neeg siv khoom thoob ntiaj teb, thiab nws cov khoom ruaj khov thiab cov txiaj ntsig tseem ceeb tau txais cov lus pom zoo los ntawm cov neeg siv khoom txawv teb chaws.Yog tias koj xav tau cov ntsiab lus ntxiv, thov hu rau ntawmsales@kintaibio.com!
