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Oct 21, 2024

Puas yog Ampelopsin muaj kev nyab xeeb rau kev noj?

Ampelopsin, tseem hu ua dihydromyricetin (DHM), yog lub ntuj tsim muaj nyob hauv rattan tshuaj yej tsob nroj thiab tau txais kev saib xyuas rau nws cov txiaj ntsig kev noj qab haus huv. Raws li cov neeg siv khoom txaus siab rau cov khoom siv ntuj tsim, cov lus nug txog kev nyab xeeb thiab kev ua tau zoo ntawm ampelopsin tau tshwm sim. Cov ntawv blog no delves rau hauv kev tshawb fawb tam sim no nyob ib puag ncig ampelopsin qhov kev nyab xeeb profile, tshawb xyuas nws cov txiaj ntsig zoo, muaj txiaj ntsig zoo, thiab pom zoo siv. Peb yuav tshuaj xyuas cov kev tshawb fawb txog kev tshawb fawb, cov kev xav ntawm cov kws tshaj lij, thiab cov kev txiav txim siab txog kev tswj hwm los muab cov ntsiab lus dav dav ntawm ampelopsin kev nyab xeeb rau kev noj, pab koj txiav txim siab paub txog kev koom ua ke no hauv koj txoj kev noj qab haus huv.

 

98% Ampelopsin dihydromyricetin (DHM)

 

Nkag siab Ampelopsin: Cov Khoom thiab Qhov Chaw

 

Chemical Structure thiab Classification

Ampelopsin belongs rau tsev neeg flavonoid, tshwj xeeb tshaj yog cov subclass ntawm flavanonols. Nws cov mis molecular yog C15H12O8, thiab nws muaj cov qauv tshwj xeeb uas ua rau nws cov khoom siv bioactive. Cov tshuaj muaj ntau pawg hydroxyl, uas ua lub luag haujlwm tseem ceeb hauv nws cov peev xwm antioxidant. Nkag siab txog cov tshuaj lom neeg ntawm ampelopsin yog qhov tseem ceeb rau kev nkag siab nws cov kev cuam tshuam hauv tib neeg lub cev thiab nws qhov cuam tshuam txog kev nyab xeeb.

 

Chemical Structure And Classification for  Ampelopsin dihydromyricetin (DHM)

 

 

Ntuj qhov chaw ntawm Ampelopsin

Thaum ampelopsin feem ntau cuam tshuam nrog cov tshuaj yej tsob ntoo (Ampelopsis grossedentata), nws tuaj yeem pom nyob rau hauv lwm hom nroj tsuag thiab. Qee qhov chaw ntxiv muaj xws li:

Hovenia dulcis (Japanese raisin ntoo)

Cedrus deodara (Himalayan cedar)

Vitis vinifera (hom txiv hmab txiv ntoo vine)

 

Natural Sources Of Ampelopsin

 

Siv keeb kwm siv tshuaj hauv tshuaj

 

Ampelopsin muaj keeb kwm ntev ntawm kev siv tshuaj hauv Suav tshuaj, tshwj xeeb tshaj yog nyob rau hauv daim ntawv ntawm rattan tshuaj yej. Nws tau ua haujlwm ib txwm ua los daws ntau yam mob, suav nrog:

Mob siab

Cawv-txoj kev tsis xis nyob

Kev mob

oxidative kev nyuaj siab

 

Kev Nyab Xeeb Profile ntawm Ampelopsin: Kev Tshawb Fawb Txog Kev Noj Qab Haus Huv thiab Kev Ntsuam Xyuas Kev Nyab Xeeb

 

Ntau qhov kev tshawb fawb tau ua los ntsuas kev nyab xeeb profile ntawm ampelopsin. Ib qho kev ntsuam xyuas toxicological uas tau luam tawm nyob rau hauv Phau Tsom Faj Txog Kev Ua Liaj Ua Teb thiab Khoom Noj Chemistry tau pom tias cov khoom lag luam pom muaj kev mob toxicity tsawg hauv cov qauv tsiaj. Txoj kev tshawb no tau tshaj tawm tsis pom qhov tshwm sim tsis zoo ntawm koob tshuaj txog 5000 mg / kg lub cev hnyav hauv nas. Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias kev tshawb fawb tsiaj tej zaum yuav tsis txhais ncaj qha rau tib neeg kev nyab xeeb, thiab xav tau kev tshawb fawb ntxiv los tsim cov txheej txheem kev nyab xeeb rau tib neeg mus sij hawm ntev.

 

Muaj peev xwm siv tshuaj yeeb

Raws li nrog ntau cov tshuaj bioactive, ampelopsin muaj peev xwm cuam tshuam nrog qee yam tshuaj. Kev tshawb fawb luam tawm nyob rau hauv European Journal of Drug Metabolism thiab Pharmacokinetics qhia tias ampelopsin tuaj yeem cuam tshuam qee yam cytochrome P450 enzymes, uas yog lub luag haujlwm rau metabolizing ntau yam tshuaj. Qhov kev sib cuam tshuam no tuaj yeem hloov pauv qhov ua tau zoo lossis kev phiv ntawm qee cov tshuaj. Cov tib neeg noj cov tshuaj yuav tsum sab laj nrog lawv tus kws kho mob ua ntej muab cov tshuaj ampelopsin rau hauv lawv cov kev tswj hwm kom tsis txhob muaj teeb meem uas tsis tau pom dua.

 

Dosage Considerations thiab Recommended Intake

 

Kev noj tshuaj kom zoo ntawm ampelopsin tseem yog ib qho kev sib cav ntawm kev tshawb nrhiav. Ntau qhov kev tshawb nrhiav tau tshuaj xyuas cov kev ntsuas sib txawv, txawm hais tias txoj hauv kev uas cov thawj coj tseem tsis tuaj yeem zoo li nteg tawm txoj cai kev noj haus txhua hnub. Piv txwv li, ib qho kev kho mob tseem ceeb tau nthuav tawm hauv Phytomedicine qhov tseeb tias koob tshuaj mus ntawm 300 mus rau 1200 mg txhua hnub tsis ua tiav qhov kev xaiv loj heev. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov lus teb ntawm tus kheej tuaj yeem sib txawv, thiab thaum txiav txim siab qhov tsim nyog npaum li cas, lub cev hnyav, tag nrho cov kev noj qab haus huv, thiab kev siv tshuaj noj ib txhij yuav tsum tau muab coj los xav.

 

Cov txiaj ntsig muaj peev xwm thiab kev xav rau Ampelopsin Consumption

 

Antioxidant thiab Anti-inflammatory Properties

Ib qho ntawm feem ntau cov txiaj ntsig tau sau tseg ntawm ampelopsin yog nws cov haujlwm muaj zog antioxidant. Ib txoj kev tshawb fawb luam tawm nyob rau hauv Oxidative Medicine thiab Cellular Longevity tau qhia tias ampelopsin zoo tshem tawm cov dawb radicals thiab txo oxidative kev nyuaj siab hauv cellular qauv. Qhov peev xwm antioxidant no tuaj yeem ua lub luag haujlwm hauv nws qhov muaj peev xwm tiv thaiv kev tiv thaiv ntau yam kab mob. Tsis tas li ntawd, kev tshawb fawb qhia tau hais tias ampelopsin kuj muaj cov tshuaj tiv thaiv kab mob, uas tuaj yeem pab tswj cov mob.

 

Antioxidant And Anti-Inflammatory Properties For Ampelopsin

 

Kev tiv thaiv daim siab thiab cawv cuam tshuam

Ampelopsin tau txais kev xav ntau heev vim nws tuaj yeem tiv thaiv lub siab los ntawm kev puas tsuaj los ntawm kev siv cawv. Kev tshuaj xyuas uas tau muab faib rau hauv kev quav cawv: Kev Tshawb Fawb Kev Tshawb Fawb thiab Kev Tshawb Fawb tau tshawb pom ampelopsin hauv cawv ua rau lub siab ua rau tsiaj ua qauv. Cawv dehydrogenase thiab aldehyde dehydrogenase proteins, uas yog lub luag haujlwm rau kev siv cawv, zoo li yuav tsum tau txhim kho los ntawm kev sib xyaw ua ke ntawm kev txhim kho hauv kev txav mus los. Ampelopsin yuav tsum tsis txhob siv los ua kev kho mob rau kev siv cawv los yog kev tiv thaiv kev tiv thaiv kev haus cawv ntau dhau, txawm tias cov kev tshawb pom no txhawb nqa. Rau kev nyab xeeb thiab kev noj qab haus huv tag nrho, lub luag haujlwm haus dej haus thiab kev sib haum xeeb tseem ceeb heev.

 

Liver Protection of dihydromyricetin (DHM)

 

 

Metabolic Health and Weight Management

Kev tshawb fawb tam sim no qhia tias ampelopsin tuaj yeem muaj txiaj ntsig zoo rau kev noj qab haus huv hauv metabolic thiab tswj qhov hnyav. Ib txoj kev tshawb fawb luam tawm nyob rau hauv Phau ntawv Journal of Nutritional Biochemistry pom tau hais tias ampelopsin supplementation nyob rau hauv nas noj cov zaub mov uas muaj roj ntau ua rau kev txhim kho ntawm insulin rhiab heev thiab txo lub cev qhov hnyav. Cov teebmeem no tau raug ntaus nqi los ntawm kev sib txuas lub peev xwm los hloov kho lipid metabolism thiab txhim kho kev siv hluav taws xob. Thaum cov txiaj ntsig no tau cog lus tseg, tib neeg kev sim tshuaj yuav tsum tau ua kom paub tseeb tias cov txiaj ntsig muaj peev xwm no thiab tsim kom muaj ntau npaum li cas rau kev noj qab haus huv metabolic. Nws yog ib qho tseem ceeb rau kev mus cuag ampelopsin raws li qhov muaj peev xwm ntxiv rau kev noj qab haus huv thiab kev ua neej nyob, tsis yog ib qho kev daws teeb meem rau kev tswj qhov hnyav lossis cov teeb meem metabolic.

 

Weight Management of dihydromyricetin (DHM)

 

 

Xaus

 

Kev tshawb fawb tam sim no qhia tias ampelopsin feem ntau muaj kev nyab xeeb rau kev noj thaum siv kom tsim nyog. Txawm li cas los xij, ib yam li lwm yam ntxiv, cov lus teb ntawm tus kheej yuav txawv, thiab kev cuam tshuam nrog cov tshuaj yuav tsum raug txiav txim siab. Thaum nws qhia tau hais tias kev cog lus hauv ntau daim ntawv thov kev noj qab haus huv, kev tshawb fawb tib neeg xav tau ntau dua los tsim kom muaj nws qhov kev nyab xeeb thiab kev noj qab haus huv zoo. Cov neeg siv khoom txaus siab koom nrog ampelopsin rau hauv lawv txoj kev noj qab haus huv yuav tsum sab laj nrog cov kws kho mob thiab paub txog kev tshawb fawb tsis tu ncua hauv daim teb no. Yog tias koj xav tau cov ntaub ntawv ntau ntxiv txog cov khoom no, koj tuaj yeem tiv tauj peb ntawmsales@kintaibio.com.

 

Cov ntaub ntawv

1. Chen, S., et al. (2019). "Dihydromyricetin: Kev tshuaj xyuas ntawm kev txheeb xyuas thiab kev ua kom muaj nuj nqis, kev ua haujlwm lom neeg, tshuaj lom neeg ruaj khov, cov metabolism thiab cov txheej txheem los txhim kho nws cov bioavailability." Trends in Food Science & Technology, 91, 586-597. https://www.sciencedirect.com/science/article/pii/S0924224418304552

2. Shen, Y., et al. (2012). "Dihydromyricetin ua cov tshuaj tiv thaiv cawv cawv tshiab." Phau ntawv Journal of Neuroscience, 32(1), 390-401. https://www.jneurosci.org/content/32/1/390

3. Hu, X., et al. (2015). "Bioavailability thiab pharmacokinetic kev tshawb fawb ntawm dihydromyricetin hauv nas ntshav los ntawm UPLC-MS / MS." Phau ntawv Journal of Pharmaceutical and Biomedical Analysis, 107, 142-148. https://www.sciencedirect.com/science/article/pii/S0731708514005627

4. Zhang, Y., et al. (2018). "Dihydromyricetin txhim kho cov piam thaj hauv cov leeg nqaij pob txha thiab txhawb nqa cov tshuaj insulin tso tawm hauv pancreatic-cells ntawm insulin receptor substrate 1." Acta Pharmacologica Sinica, 39(2), 234-242. https://www.nature.com/articles/aps201758

5. Liao, W., et al. (2014). "Metabolic profiles ntawm dihydromyricetin hauv nas los ntawm UPLC-Q-TOF / MS." Phau ntawv Journal of Chromatography B, 971, 71-76. https://www.sciencedirect.com/science/article/pii/S1570023214006060

6. Qi, S., et al. (2017). "Ampelopsin txo qis endothelial hyperpermeability los ntawm inhibiting cov haujlwm ntawm VE-cadherin phosphorylation." Phau ntawv Journal of Cellular Biochemistry, 118(12), 4828-4838. https://onlinelibrary.wiley.com/doi/abs/10.1002/jcb.26155

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