Part1. Dab tsi yog qhov txiaj ntsig ntawm bacopa monnieri extract?
Bacopa monniera extract yog muab rho tawm thiab ua tiav los ntawm tag nrho cov nroj tsuag ntawm Bacopa monniera, ib tsob nroj ntawm genus Bacopa monniera hauv tsev neeg Scrophulariaceae, thiab feem ntau muaj triterpenoid saponins. Nws muaj cov haujlwm pharmacological xws li txhim kho kev nco, sedative, antiepileptic, anti-inflammatory, antipyretic thiab analgesic.
Ntu 2. Pharmacological teebmeem
1. Pharmacological kev ua ntawm cov hlab ntsha
(1) Muaj txiaj ntsig zoo rau kev kawm thiab kev nco
Kev tshawb fawb tau pom tias Bacopa monnieri thiab nws cov extracts muaj cov teebmeem hauv hlwb. Bacopa monnieri thiab nws cov ethanol extract tuaj yeem txhim kho kev muaj peev xwm kawm tau zoo, thiab kev txhawb nqa kev paub txog kev ua haujlwm feem ntau yog vim muaj ob qho saponins ntawm Bacopa monnieri saponin A thiab B hauv ethanol extract. Ntxiv nrog rau kev txhawb nqa kev kawm ib txwm muaj thiab kev nco ua haujlwm, cov khoom muaj txiaj ntsig tseem tuaj yeem cuam tshuam kev tsis nco qab (tsis nco qab) vim yog scopolamine, hluav taws xob poob siab thiab tswj kev ntxhov siab.
(2) Kev tiv thaiv kev ntxhov siab
Bacopa monnieri extract yog txawv ntawm benzodiazepine anxiolytics, tus qub tuaj yeem txhim kho kev txawj ntse thaum tsim cov nyhuv anxiolytic, thaum tom kawg muaj kev phiv los ntawm kev ua rau dementia. Cov tshuaj tiv thaiv kev ntxhov siab ntawm cov koob tshuaj Bacopa monnieri extract muaj zog dua, pom tseeb zoo dua LZP. Bacopa monnieri tsis tsuas yog tsis ua rau dementia, tab sis tuaj yeem txhim kho lub cim xeeb ntawm cov tsiaj txhu thiab tib neeg.
(3) Antidepressant nyhuv
Methanol txheem extract ntawm Bacopa monniera muaj ib tug muaj zog antidepressant nyhuv ntawm nas kev nyuaj siab qauv, piv nrog antidepressant imipramine (15mg / kg), nyob rau hauv yuam ua luam dej thiab tau txais kev pab tsis muaj kev nyuaj siab qauv muab niaj hnub sham Purslane 20 los yog 40mg / kg ib zaug, nruam tswj rau 5 hnub. , tuaj yeem tsim cov nyhuv antidepressant pom tseeb.
(4) Anticonvulsant nyhuv
Bacopa monnieri tau siv ib leeg lossis ua ke nrog phenytoin (ib qho tshuaj tiv thaiv kab mob uas ua rau kev paub tsis meej). Kev ntsuas kev zam tsis dhau, qhov siab tshaj plaws ntawm electroshock qaug dab peg thiab lub cev muaj zog hauv cov nas tau raug soj ntsuam. Cov txiaj ntsig tau pom tias phenytoin tuaj yeem cuam tshuam kev txawj ntse. muaj nuj nqi, thiab Bacopa monnieri tuaj yeem thim rov qab qhov tsis zoo ntawm phenytoin ntawm kev paub txog kev ua haujlwm, txhim kho kev nco tau thiab khaws cia, tab sis tsis cuam tshuam rau cov nyhuv anticonvulsant ntawm phenytoin; Bacopa monnieri siv ib leeg los yog ua ke nrog lwm cov tshuaj antiepileptic kuj tau lees tias Bacopa monnieri muaj cov nyhuv antiepileptic muaj zog, thiab tuaj yeem kho qhov kev puas tsuaj ntawm cov tshuaj antiepileptic rau kev paub txog kev ua haujlwm.
2. Cov nyhuv tiv thaiv qog
Bacopa monnieri extract tuaj yeem cuam tshuam kev loj hlob ntawm cov qog hlwb ntawm qhov tsis tshua muaj siab; cov toxicity ntawm high concentrations tseem xav tau ntxiv nyob rau hauv vivo thwmsim kom paub meej. Cov tshuaj hom kev ua haujlwm yuav yog los ntawm inhibiting DNA replication.
3. Kev tiv thaiv daim siab
Cov kev tshawb fawb tau pom tias Bacopa monniera tiv thaiv qhov inhibition ntawm antioxidant enzymes thiab txo qis glutathione qib, inhibits qhov nce ntawm lipid peroxide tom qab kev tswj hwm morphine, thiab yog li muaj cov nyhuv hepatoprotective rau morphine-induced siab lom hauv nas.
4. Relaxes cov leeg nqaij
Cov nyhuv so kom txaus los ntawm Pseudomonas tuaj yeem koom nrog cov tshuaj prostacyclin thiab -adrenergic receptors. Tsis tas li ntawd, cov nyhuv so no tsis nyob ntawm qhov ua kom cov endothelial thiab muscarinic receptors.
5. Lwm cov haujlwm
Ntxiv rau cov teebmeem kev puas siab puas ntsws, tshuaj tiv thaiv kab mob, cardiotonic thiab lwm yam teebmeem tshuaj ntawm Bacopa monnieri npaj los yog rho tawm kuj tau soj ntsuam. Cov nyhuv ntawm Bacopa monnieri ntawm inhibiting kev sim o tau muab piv nrog cov tshuaj tiv thaiv kab mob indomethacin, thiab cov txiaj ntsig tau pom tias BM tau zoo inhibited kev sim tshuaj tiv thaiv los ntawm inhibiting prostaglandin synthesis thiab ib feem stabilizing lysosomal daim nyias nyias, Thiab Bacopa monniera tsis ua rau mob plab hnyuv. ntawm cov tshuaj tiv thaiv kab mob. Bacopa monniera extract tuaj yeem kho ntau hom mob.
Ntu 3. Clinical kev ua tau zoo
Xwm thiab tsw me ntsis qab zib, lub teeb, txias. Nws muaj cov teebmeem ntawm tshem tawm cov cua sov thiab txias cov ntshav, detoxifying thiab txo qhov o. Rau cov kab mob dysentery, conjunctival congestion thiab o mob, erysipelas, hemorrhoid o thiab mob, sab nraud daim ntawv thov tswj tus ntxhw.
