Part1. Dab tsi yogtshuaj yej dub extract theaflavins?
Theaflavin, cov xim daj daj muaj nyob hauv cov tshuaj yej dub, yog cov khoom ntawm tshuaj yej fermentation. Hais txog biochemistry, theaflavin yog ib yam khoom nrog polyphenolic hydroxyl pawg thiab phenolic ketone qauv. Nws yog thawj qhov sib xyaw nrog cov txiaj ntsig pharmacological pom los ntawm tshuaj yej. Theaflavins muaj li ntawm 0.5 feem pua rau 2 feem pua ntawm qhov hnyav ntawm cov tshuaj yej qhuav, nyob ntawm seb cov tshuaj yej dub ua li cas. Thea yellow pigment plays lub luag haujlwm hauv cov xim ci thiab muaj zog saj ntawm tshuaj yej kua zaub, thiab yog qhov tseem ceeb ntawm cov tshuaj yej dub.
Ntu 2. Keeb kwm ntawm theaflavins
Theaflavin tau pom thawj zaug los ntawm Roberts. Nws hais txog cov txiv kab ntxwv-daj tshuaj yaj hauv ethyl acetate hauv cov tshuaj yej dub. Nws yog tsim los ntawm oxidative condensation ntawm polyphenols thiab lawv cov derivatives. Cov ntsiab lus ntawm theaflavin hauv cov tshuaj yej dub feem ntau yog 0.3 feem pua rau 1.5 feem pua. , plays lub luag hauj lwm txiav txim siab nyob rau hauv cov xim, ntxhiab thiab zoo ntawm cov tshuaj yej dub. Nyob rau hauv xyoo tas los no, vim qhov tseeb tias theaflavin muaj ntau lub peev xwm ua haujlwm ntsig txog tib neeg kev noj qab haus huv, xws li tshuaj tiv thaiv oxidation, tiv thaiv thiab kho cov kab mob plawv, txo cov ntshav rog, tiv thaiv qog noj ntshav thiab tiv thaiv qog noj ntshav, thiab lwm yam, nws tau txais. Kev saib xyuas thoob plaws hauv tsev thiab txawv teb chaws, thiab tau dhau los ua cov khoom tseem ceeb hauv tshuaj yej zoo chemistry thiab kev ua haujlwm. Composition kev tshawb fawb hotspots.
Ntu 3. Cov ntsiab lus tseem ceeb ntawm theaflavins
Theophylline yog tsim los ntawm polyphenols thiab catechins, thiab tseem muaj cov amino acids, vitamin C, vitamin E, provitamin A, flavonoids thiab flavonols. Theaflavin yog cov khoom tseem ceeb ntawm theophylline, thiab muaj 12 cov khoom hauv tag nrho, suav nrog theaflavin, theaflavin-3-gallate, theaflavin-3,3'-digallate thiab theaflavin-3 '-Gallate yog cov plaub qhov tseem ceeb tshaj plaws theaflavins. Hauv kev ua tshuaj yej, nws yog tsim los ntawm kev sib koom ua ke oxidation condensation ntawm yooj yim catechin thiab gallocatechin. Kev tshawb pom ntawm theaflavins yog ze ze rau kev tshawb fawb ntawm cov txheej txheem fermentation ntawm cov tshuaj yej dub.
Ntu 4. Physiological muaj nuj nqi
Theaflavins muaj zog physiological kev ua ub no, xws li anti-oxidation, anti-cancer thiab anti-cancer, txo cov ntshav rog, tiv thaiv kab mob plawv, anti-bacterial thiab anti-virus thiab lwm yam physiological functions, thiab txawm muaj zog tshuaj muaj zog tshaj catechins nyob rau hauv ib co. yam.
1. Kev tiv thaiv kab mob qog noj ntshav thiab tiv thaiv kab mob qog noj ntshav
Tshuaj yej muaj cov tshuaj tiv thaiv kab mob thiab tiv thaiv qog noj ntshav, thiab nws cov khoom xyaw tseem ceeb yog tshuaj yej polyphenols, catechin monomers thiab tshuaj yej pigments. Cov kev tshawb fawb tshuaj niaj hnub no tau pom tias theaflavins muaj kev tiv thaiv kev hloov pauv, inhibition ntawm cytochrome P450 kev ua haujlwm, inhibition ntawm extracellular signaling thiab proliferation ntawm cov qog nqaij hlav cancer, tiv thaiv kab mob thiab chemoprevention ntawm cancer, thiab lwm yam. Raws li cov ntaub ntawv qhia, tshuaj yej pigment muaj zog antioxidant zog. tshaj li tshuaj yej polyphenols thiab kev kho mob zoo thiab kev noj qab haus huv muaj nuj nqi, xws li tiv thaiv kab mob plawv thiab cerebrovascular, tiv thaiv cov hniav caries, tiv thaiv kab mob cancer thiab anticancer, antibacterial thiab antiviral, thiab lwm yam.
2. Antioxidant nyhuv
Theaflavins ua tiav nws cov txiaj ntsig antioxidant los ntawm kev tswj hwm cov haujlwm ntawm cov enzymes lom hauv lub cev, ncaj qha tshem tawm cov dawb radicals, complexing nrog hlau ions, thiab tiv thaiv oxidation ntawm cov lipoproteins tsawg.
3. Anti-inflammatory
Tshuaj yej pigment tuaj yeem txo qhov tsim ntawm endogenous uric acid, txo qhov pib ntawm gouty mob caj dab, thiab hauv qee qhov kev hwm yog superior rau probenecid thiab allopurinol.
4. Tshuaj tua kab mob
Friedman M et al. kawm txog cov tshuaj tua kab mob ntawm 7 hom catechin monomers, 4 hom theaflavins tseem ceeb thiab cov dej tsis zoo ntawm ntau yam tshuaj yej ntawm Bacillus cereus. Cov txiaj ntsig tau pom tias cov tshuaj tua kab mob ntawm cov tshuaj yej feem ntau yog nyob ntawm cov tshuaj yej nplooj catechins thiab theaflavins, thiab cov nyhuv antibacterial tshaj li cov tshuaj tua kab mob xws li tetracycline thiab vancomycin.
5. Anti-virus
1 hli concentration ntawm cov tshuaj yej dub tuaj yeem tiv thaiv tus kab mob khaub thuas A thiab kab mob khaub thuas B mus rau lub raum MDCK hlwb, thiab nws cov txheej txheem yog inhibit qhov adsorption ntawm cov kab mob ntawm cov hlwb es tsis txhob cuam tshuam cov kab mob sib kis hauv cov hlwb. Tsis tas li ntawd, nws tau pom tias TF-3 tuaj yeem cuam tshuam tus kab mob ntawm lub raum liab MA104 cell kab rau rotavirus thiab enterovirus, TFs tuaj yeem ua rau tus kab mob bovine thiab tus mob coronavirus tsis zoo, thiab 80mg / ml dub tshuaj yej extract tuaj yeem cuam tshuam tag nrho. Tib neeg rotavirus Virus.
6. Tshuaj tiv thaiv kab mob plawv
TFs muaj cov tshuaj tiv thaiv kev coagulation tseem ceeb, fibrinolysis, thiab tiv thaiv platelet adhesion thiab aggregation, thiab tuaj yeem txo qis triglyceride GT hauv cov ntshav ntawm cov tsiaj rog. Cov txheej txheem yog los ntawm kev txhim kho cov ntshav liab deformability, kho cov ntshav liab aggregation, thiab platelet adhesion. Kev sib sau ua ke, txo cov ntshav viscosity, txhim kho microcirculation, ua kom cov ntaub so ntswg cov ntshav thiab oxygen, txhim kho lub cev tag nrho kev tiv thaiv thiab cov ntaub so ntswg metabolism, ua tiav lub hom phiaj ntawm kev tiv thaiv kab mob thiab kev kho mob, thiab tuaj yeem txo qis qib ntawm triglyceride hauv cov ntshav siab. Cov tsiaj rog, Tsawg-density lipoprotein LDL, nce high-density lipoprotein HDL. TFs muaj cov nyhuv inhibitory tseem ceeb ntawm angiotensin I-hloov enzyme, thiab muaj txiaj ntsig zoo rau ntshav.
7. Deodorization
Theaflavins tuaj yeem tshem tawm ua pa tsis zoo. Nyob rau hauv cov xwm txheej alkaline ntawm PH10, 1 mg ntawm theaflavins nrog cov ntsiab lus ntawm 40 feem pua tuaj yeem tshem tawm 0.232 mg ntawm methyl mercaptan.
