Senna yog ib tsob nroj paj uas tau siv rau hauv tshuaj ntsuab tshuaj ntsuab rau ntau pua xyoo. Kev npaj ua los ntawm senna nplooj thiab pods tau ntev tau noj raws li ib tug natural laxative los txo cov cem quav thiab txhawb lub plab zom mov. Hnub no,senna qhuav extracttseem yog ib qho tshuaj uas nrov tshaj plaws hauv khw muag khoom los txhawb kev noj qab haus huv ntawm plab hnyuv thiab kho qee zaum cem quav. Tsab ntawv xov xwm no tshawb txog cov kev qhia siv thiab kev xav txog kev siv senna qhuav extract, raws li kev pom los ntawm cov chaw kho mob thiab cov ntaub ntawv tshawb fawb.
Nkag siab Senna Dry Extract
Senna belongs rau tsev neeg Fabaceae ntawm paj ntoo. Muaj ntau tshaj 250 hom senna, tab sis Cassia senna (tseem hu ua Alexandrian lossis Khartoum senna) thiab Cassia angustifolia (tseem hu ua Tinnevelly lossis Indian senna) feem ntau yog siv los tsim senna qhuav extract. Cov nplooj thiab cov pods ntawm cov nroj tsuag senna muaj cov tshuaj lom neeg hu ua anthraquinones, uas xav tias yog lub luag haujlwm rau senna cov tshuaj laxative.
Anthraquinones zoo li rhein, aloe-emodin, emodin, chrysophanol, thiab physcion muaj nyob rau hauv senna nplooj thiab pods. Lawv tsim cov chav kawm ntawm cov tebchaw hu ua sennosides, tshwj xeeb tshaj yog sennoside A thiab sennoside B. Cov tebchaw no muaj cov qauv peb-ntiv nplhaib nrog ntau pawg hydroxy.
Senna qhuav extract yog ib qho kev npaj ua los ntawm senna nplooj thiab pods. Nws muaj cov tshuaj anthraquinones ntau dua li cov khoom siv raw. Senna qhuav extract nkoos contractions nyob rau hauv txoj hnyuv loj uas pab ua kom lub plab zom mov thiab ua kom cov quav ntim thiab cov kua dej hauv cov hnyuv. Qhov no pab txo cem quav los ntawm kev txhawb nqa defecation.
Qhia siv Senna qhuav Extract
Feem ntau cov tsoos thiab niaj hnub no siv senna qhuav extract yog raws li ib tug luv luv lub sij hawm laxative rau relieving cem quav thiab irregular plob tsis so tswj. Ntawm cov saum toj kawg nkaus Google nrhiav tau rausenna qhuav extract, cov koom haum tswj hwm zoo li FDA thiab cov vev xaib xws li WebMD, Drugs.com, thiab Healthline txhua tus hais txog kev siv senna npaj rau qee zaus cem quav.
Qee qhov kev tshawb fawb ua ntej tseem qhia tau tias muaj peev xwm rau senna extract los txhawb kev noj qab haus huv ntawm plab hnyuv. Raws li ib txoj kev tshawb fawb, senna extract tau nthuav tawm cov tshuaj tua kab mob tiv thaiv qee cov kab mob uas tuaj yeem ua rau muaj teeb meem hauv plab xws li E.coli, S.aureus, P. mirabilis, thiab S. typhi. Txawm li cas los xij, tseem xav tau kev tshawb fawb ntxiv.
Nyob rau hauv Indian Ayurvedic thiab tsoos suav tshuaj systems, senna tshuaj yej thiab kev npaj yog siv los daws cov kev tsis txaus siab ntawm digestive ib ntsuj av, gases, tsam plab thiab tsis qab los noj mov. Txawm li cas los xij, cov pov thawj kho mob tam sim no tsis txaus los pom zoo senna rau cov kev siv no.
Mechanism ntawm Action
Thaum noj qhov ncauj, sennosides thiab lwm yam sib txuas hauv senna qhuav extract hla cov hnyuv tsis tau nqus mus rau hauv cov hlab ntsha. Anthraquinone glycosides hauv senna yog tom qab ntawd hloov los ntawm cov kab mob plab hnyuv mus rau hauv cov metabolites uas ncaj qha txhawb cov hlab ntsha hauv txoj hnyuv.
Qhov no nce propulsive colonic lub cev muaj zog ua haujlwm thiab ua kom lub plab zom mov nrawm. Txoj hnyuv loj yog qhib kom cog lus ntau zaus, ua kom lub plab zom mov sai. Senna kuj tseem pab txo cov quav thiab ua kom lub plab ntim thiab cov kua dej hauv cov hnyuv, ua kom yooj yim dua. Nws hloov cov electrolyte thiab dej reabsorption thiab secretion nyob rau hauv lub colonic mucosa thiab.
Cov teebmeem no txo qis cem quav los ntawm kev txhawb nqa defecation. Ntau qhov kev tshawb fawb soj ntsuam txhawb nqa senna qhov ua tau zoo rau kev txo qis qis qis. Ib qho kev tshuaj xyuas pom tau pom senna los txhim kho plab hnyuv ntau zaus, sib xws, straining, tsam plab thiab plab tsis xis nyob.
Daim ntawv ntawm kev tswj hwm
Senna qhuav extractFeem ntau muaj nyob rau hauv ntsiav tshuaj, tshuaj ntsiav thiab granule formulations yuav tsum tau noj qhov ncauj. Cov tshuaj yej senna tshuaj yej npaj kuj muaj ntau. Standardized senna extract kom ntseeg tau cov ntsiab lus sennoside.
Cov koob tshuaj pom zoo tuaj yeem sib txawv raws li hnub nyoog thiab kev tsim qauv tab sis cov lus qhia siv tshuaj senna qhuav rau cov neeg laus poob rau hauv thaj tsam ntawm 300-500mg txhua hnub, noj ib zaug ib hmos lossis faib ua ob zaug txhua hnub. Nws cov teebmeem tuaj yeem pom tau 6-12 teev tom qab noj. Cov nyhuv laxative feem ntau kav ntev 6-12 teev.
Kev noj sennosides ntev ntev los yog ntau dhau tuaj yeem ua rau mob raws plab thiab cuam tshuam hauv qib electrolyte yog li kev noj haus yuav tsum txwv tsawg dua ib lub lis piam ib zaug. Nco ntsoov ua raws li cov lus qhia noj tshuaj thiab sab laj nrog kws kho mob rau kev siv kom tsim nyog.
Kev nyab xeeb thiab kev txiav txim siab
Rau cov neeg laus noj qab haus huv feem ntau, senna tuaj yeem siv nyab xeeb raws li kev pab cuam cem quav. Txawm li cas los xij nws yog ib txwm muaj txiaj ntsig rau kev ceev faj ua ntej siv senna qhuav extract tshuaj lossis tshuaj yej.
Cov kev mob tshwm sim tuaj yeem muaj xws li mob plab thiab tsis xis nyob, raws plab, lub cev qhuav dej, cov leeg tsis muaj zog thiab mob siab rau lub siab. Kev tsim txom lub sij hawm ntev nrog kev npaj senna tuaj yeem cuam tshuam txoj hnyuv ua haujlwm ntev. Qhov no tuaj yeem ua rau laxative dependence nyob rau qee kis.
Cov neeg uas muaj mob plab xws li IBS, Chron's disease lossis ulcerative colitis, kab mob raum, electrolyte imbalances thiab qee cov tshuaj yuav tsum tsis txhob siv senna tshwj tsis yog tias pom zoo los ntawm kws kho mob. Cov poj niam cev xeeb tub thiab cov poj niam laus yuav tsum tsis txhob siv senna vim tsis muaj cov ntaub ntawv kev nyab xeeb thiab kev pheej hmoo ntawm lub cev qhuav dej lossis raws plab.
Cov kab mob ntawm daim siab toxicity tau raug tshaj tawm txawm tias muaj kev kho mob kom tsim nyog yog li nws tseem ceeb heev kom ua tib zoo ua raws li cov lus qhia siv thiab saib xyuas qhov tsis zoo. Tham nrog kws kho mob ua ntej sivsenna qhuav extractyog tias koj muaj teeb meem kev noj qab haus huv hauv qab lossis tab tom noj cov tshuaj noj kom tsis txhob muaj teeb meem.
Herbal Supplement Considerations
Zoo li nrog cov tshuaj ntsuab ntxiv, nws yog ib qho tseem ceeb rau qhov chaw senna extract khoom los ntawm cov tuam txhab muaj koob npe. Kev noj zaub mov tsis raug tswj hwm tib txoj kev nruj raws li cov tshuaj hauv ntau lub teb chaws, yog li qhov zoo tuaj yeem sib txawv ntawm cov hom.
Xaiv cov khoom lag luam zoo los ntawm cov tuam txhab tsim khoom ntxiv tuaj yeem pab txo qis kev pheej hmoo ntawm kev sib kis lossis kev deev deev. Nws tseem yog ib qho tseem ceeb kom qhia rau koj tus kws kho mob txog txhua yam tshuaj ntsuab uas koj noj kom tso cai rau kev soj ntsuam ntawm cov tshuaj ntsuab-tshuaj cuam tshuam.
Qee cov tshuaj senna extract kuj muaj cov tshuaj ntxiv xws li cascara, aloe, rhubarb lossis frangula. Cov formulations sib xyaw no tuaj yeem ua rau muaj zog tab sis tuaj yeem ua kom muaj kev pheej hmoo ntawm kev tsis zoo. Ua tib zoo tshuaj xyuas cov khoom xyaw thiab ib txwm ua raws li cov lus qhia noj.
Senna extract potency kuj tuaj yeem sib txawv heev nyob ntawm txoj kev ua. Extracts npaj siv cov kuab tshuaj xws li ethanol zoo mloog zoo rau active sennosides. Tab sis cov kua dej cawv yuav tsis haum rau qee yam kev ntseeg, kab lis kev cai lossis kev nyiam ntawm tus kheej.
Kev sib piv
Piv nrog rau lwm cov tshuaj laxatives hauv khw muag khoom xws li magnesium hydroxide (mis nyuj ntawm magnesia), polyethylene glycol (Miralax), thiab bisacodyl (Dulcolax), senna tuaj yeem muab kev siv lub sijhawm luv luv rau cem quav nrog qhov pib ua haujlwm sai.
Txawm li cas los xij, thaum PEG laxatives pom tau tias muaj kev nyab xeeb heev rau kev siv ntev, senna tsuas yog pom zoo rau kev siv ib ntus vim muaj kev pheej hmoo ntawm cov kev mob tshwm sim ntev dua xws li raws plab, lub cev qhuav dej thiab kev ua haujlwm ntawm cov hnyuv hauv lub sijhawm. Dulcolax kuj tseem yuav hnyav dua li senna, nrog ntau dua qhov ua rau mob plab raws li qhov tshwm sim.
Yog li rau qee zaus cem quav, senna extract muaj qhov sib npaug ntawm kev ua tau zoo thiab kev nyab xeeb thaum siv los ntawm kev xav. Tab sis cov uas tawm tsam nrog cov teeb meem cem quav tsis tu ncua yuav xav tshawb xyuas cov tshuaj osmotic laxatives zoo li Miralax thiab magnesium hydroxide rau kev siv txhua hnub.
Yav tom ntej Outlook
Thaum senna muaj keeb kwm ntev ntawm kev siv tshuaj, niaj hnub kev paub txog tshuaj ntsuab no tseem nthuav dav. Kev tshawb fawb tsis ntev los no tau tshawb nrhiav cov tshuaj pharmacokinetics, pharmacodynamics, toxicology thiab mechanism ntawm kev txiav txim ntawm cov ntsiab lus tseem ceeb hauv senna zoo li anthraquinones.
Cov txheej txheem qib siab xws li HPLC ntiv tes profileing kuj tau ua kom muaj cov ncauj lus kom ntxaws tshuaj xyuas thiab kev ua qauv ntawm kev lag luam senna npaj. Thiab cov txheej txheem tsim tawm tshiab xws li microencapsulation tuaj yeem txo qhov hloov pauv thaum txhim kho kev ruaj ntseg thiab tswj kev tso tawm.
Xaus
Senna qhuav extractfeem ntau yog siv los pab txhawb lub plab zom mov thiab txo cov cem quav. Nws tau pom tias muaj cov nyhuv laxative hauv ntau qhov kev tshawb fawb thiab tseem muaj dav dav raws li kev pab cuam digestive hauv khw muag khoom. Txawm li cas los xij nws tseem ceeb heev kom xav txog cov kev mob tshwm sim thiab zam kev siv ntev yam tsis muaj kev qhia kho mob.
Rau qee zaus cem quav, senna yuav yog ib qho kev xaiv zoo thaum siv lub luag haujlwm raws li kev saib xyuas ntawm tus kws kho mob. Tab sis ib yam li lwm yam ntxiv, nrog koj tus kws kho mob tham ua ntej siv senna qhuav extract los txiav txim seb nws puas tsim nyog rau koj tus kheej xav tau kev noj qab haus huv.
PebSenna qhuav Extracttau txais kev qhuas zoo los ntawm cov neeg siv khoom. Yog tias koj xav paub ntau ntxiv txog cov khoom no, thov hu rau dawbSales@Kintaibio.Com.
Cov ntaub ntawv:
[1] Morales MA, Hernández D, Bustamante S, Bach H, et al. "Senna (Cassia angustifolia Vahl.) thiab physalis (Physalis ixocarpa Brot.) extracts thiab hmoov: characterization thiab functional zog." Cog Zaub Mov Hum Nutr. 2020.
[2] Mehmood MH, Munir S, Khalid UA, Asrar M, et al. "Phytochemistry, kev siv tshuaj kho mob thiab cov khoom siv tshuaj ntawm Cassia abbreviata: Kev tshuaj xyuas." Asian Pac J Trop Med. 2017.
[3] Yang L, Ma S, Zhou S, Chen J, et al. "Kev npaj thiab kev ntsuam xyuas ntawm senna extract microcapsules." Pharmacogn Mag. 2015
[4] Jiang X, Tanaka H, Yang J, Iwamoto M, et al. "Tus cwj pwm ntawm anthraquinone derivatives los ntawm Senna obtusifolia feem los ntawm cov kua chromatography nrog ultraviolet, huab hwm coj spectrometry thiab nuclear magnetic resonance detection." J Chromatogr A. 2007.
[5] Godding EW. "Kev kho mob ntawm laxative tsim txom los ntawm gastroenterologist pom." Dtsch Med Wochenschr. Xyoo 1988.
[6] Wed. "Senna." 2022.
[7] Ibrahim MA, Sadek EM, Hendawy SF. "Antimicrobial teebmeem ntawm Cassia senna extracts tawm tsam qee cov kab mob gram tsis zoo thiab cov kab mob zoo." World Appl Sci J. 2014.
[8] Kong W, Jia G, Huang X, Wang S, et al. "Ib lub tshuab pharmacology mus kom ze ntawm senna los ntawm txoj kev xav mus rau kev kho mob hauv cov tshuaj suav tshuaj." Sci Rep. 2014.
[9] Van der Watt G, Laug SK. "Biowaiver monographs rau tam sim tso tawm cov ntaub ntawv ntawm qhov ncauj noj: sodium sennoside." J Pharm Sci. Xyoo 2009.
