Coptis Chinensis cag Extract hmoov

Xi'an Kintai Biotech Inc yog ib qho ntawm cov tuam ntxhab thiab cov muag khoom ntawm coptis chinensis cag extract hmoov hauv Suav teb. Thov koj xav tias dawb rau cov lag luam wholesale siab zoo coptis chinensis cag extract hmoov muag ntawm no los ntawm peb lub hoobkas. Rau nqe kev sab laj, tiv tauj peb.

Raws li cov chaw tsim khoom tshwj xeeb hauv siab -purity botanical extracts,KINTAIBIO^®tau mob siab rau ua haujlwm raws li koj tus neeg muab kev ntseeg siab ntawmCoptis hauv paus Extract. Peb cov khoom yog muab los ntawm cov rhizomes qhuav ntawmCoptis chinasis(ib tsob nroj ntawm tsev neeg Ranunculaceae); nws lub ntsiab active cov ntsiab lus yogBerberine Hydrochloride. Peb cov qauv specifications muaj los ntawm90%rau97% Berberine Hydrochloridecov ntsiab lus, nrog rau99%qib purity tshwj xeeb tsim los ua kom tau raws li cov kev xav tau nruj rau siab - cov ntaub ntawv zoo hauv cov khoom siv tshuaj thiab cov khoom siv. Cov khoom nthuav tawm raws li koob daj -zoo li cov muaju; Txawm hais tias cov ntsev hydrochloride tsuas yog me ntsis solubility hauv dej txias, peb cov txheej txheem tsim khoom siab heev kom ntseeg tau tias cov txiaj ntsig extract muaj qhov zoo sib xws thiab ruaj khov.

Coptis chinensis Franch

berberine hydrochloride hmoov

Tsim raws li keeb kwm dav dav ntawmCoptis hauv paus ExtractHauv Cov Tshuaj Hauv Suav Teb, cov kev tshawb fawb niaj hnub no tau lees paub nws cov txiaj ntsig tseem ceeb hauv thaj chaw xws li txo cov ntshav qabzib, tswj lipid, tiv thaiv-mob, tiv thaiv- mob qog noj ntshav, thiab txhim kho kev ua haujlwm ntawm lub paj hlwb. Los ntawm kev siv ntau yam txheej txheem- suav nrog kev hloov pauv ntawm insulin rhiab heev, txo qis ntawm insulin tsis kam, thiab kev tawm dag zog los tiv thaiv- mob thiab antioxidant teebmeem-cov extract no muaj kev txhawb nqa zoo rau kev cuam tshuam thiab kev tswj cov mob xws li ntshav qab zib, kab mob plawv thiab cerebrovascular kab mob, osteoporosis's kab mob, thiab cov kab mob osteoporosis.

1. berberine hydrochloride

2. Berberine sulfate

Tiv tauj peb tam sim no kom tau txais cov qauv dawb!

KINTAIBIO^®tau mob siab rau ntau tshaj kaum xyoo rau kev tshawb fawb thiab kev loj hlob ntawm cov khoom xyaw botanical, ruaj ntau lub teb chaws invention patents thiab ntawv pov thawj thoob ntiaj teb-suav nrogISO 9001 Daim ntawv pov thawj, ISO 22000 Daim Ntawv Pov Thawj, IP Tsis yog -GMO, Halal, thiab Organic certifications. Peb qhov kev sib tw zoo nyob hauv peb cov khoom tshwj xeeb zoo, muaj peev xwm ruaj khov tshaj 100 tons hauv ib hlis, thiab cov nqi sib tw heev. Tsis tas li ntawd, tag nrho peb cov khoom nruj me ntsis ua raws liEUthiabTeb Chaws Asmeskascov qauv zoo thiab tau lees paub los ntawm cov neeg sab nraud thib peb -cov koom haum xeem. Ntxiv rau qhov muab cov qauv - specificationCoptis extract, peb zoo siab los muab kev pabcuam customized raws li koj qhov kev xav tau tshwj xeeb. Peb caw koj hu rau peb ntawmsale@kintaibio.comthov cov qauv dawb lossis sib tham txog koj qhov kev yuav khoom.

Raw Material Pulverization thiab Acid Extraction

High -zooCoptis chinasisrhizomes raug xaiv raws li cov khoom siv raw. Tom qab ntxuav thiab ziab, cov rhizomes yog pulverized rau hauv cov hmoov coarse nrog ib tug particle loj ntawm 20-40 mesh. CovCoptis hmoovyog them rau hauv lub nkoj rho tawm, thiab 0.5% -1% dilute sulfuric acid tov yog ntxiv rau qhov txias maceration. Cov khoom -rau- kua piv yog tswj nyob rau hauv thaj tsam ntawm 1:6 txog 1:10. Cov txheej txheem rho tawm yog ua tsis tu ncua rau peb lub voj voog, nrog rau txhua lub voj voog kav ntev li 4-6 teev. Cov acidic tej yam kev mob pab txhawb kev hloov pauv ntawm berberine- cov khoom muaj nyob hauv Coptis- mus rau hauv cov ntsev soluble, yog li ua kom cov extraction tawm los ntawm cov khoom xyaw nquag. Tom qab ua tiav ntawm kev rho tawm, qhov sib tov yog raug pom thiab sib cais kom tawm los ntawm cov kua extract thiab cov khoom seem.

Dej nag thiab Extraction ntawm Crude Berberine

Hydrochloric acid yog ntxiv rau cov tshuaj extract los kho cov pH rau 1-2. Tom qab ntawd, 5%–10% sodium chloride (NaCl) yog ntxiv rau induce salting-tawm. Qhov sib tov yog tso cai rau sawv ntsug li ib teev, thaum lub sij hawm uas cov berberine maj mam precipitates los ua ib tug crude khoom. Tom qab filtration, crude berberine precipitate thiab acidic niam cawv yog sib cais. Cov kauj ruam no feem ntau yog siv cov hauv paus ntsiab lus ntawm acidification thiab salting - tawm los txhim kho kev ua kom muaj txiaj ntsig zoo ntawmua berberine, yog li tso lub hauv paus rau kev ua kom huv tom qab.

Alkalinization, Purification, thiab tshem tawm impurity

Lub crude berberine precipitate yog yaj nyob rau hauv purified dej nyob rau hauv cua sov. Tom qab ntawd, txiv qaub kua txiv yog ntxiv los kho cov pH rau 8.5-9.0. Nyob rau hauv cov xwm txheej alkaline no, impurities-tshwj xeeb yog sulfate ions-react tsim insoluble precipitates, xws li calcium sulfate, yog li tshem tawm inorganic ntsev, pigments, thiab ntau yam impurities. Tom qab filtration, calcium sulfate thiab impurity precipitates raug tshem tawm, yielding ib nrab purified.ua berberinelim.

Recrystallization thiab Refinement txheej txheem

Hydrochloric acid yog ib zaug ntxiv rau cov purified filtrate los kho cov pH mus rau 1-2, tom qab ntawd ntxiv 10% -15% sodium chloride kom induce ib tug thib ob salting - tawm. Cov txheej txheem txias thiab sawv crystallization yog tom qab ntawd ua haujlwm kom tso cai rauberberine hydrochloride hmoovkom maj mam crystallize rau hauv cov ntaub ntawv ruaj khov. Tom qab ua tiav ntawm crystallization, cov muaju yog sib cais los ntawm leej niam cawv ntawm centrifugation los yog lub tshuab nqus tsev pom los txhim kho ob qho tib si purity ntawm cov khoom kawg thiab kev ncaj ncees ntawm cov muaju.

Kev ziab, Pulverization, thiab ntim khoom

Qhov tshwm simberberine hydrochloride hmoovcrystals yog ntxuav nrog dej txias purified kom tshem tawm residual nto ntsev thiab impurities. Thaum kawg, cov khoom siv lead ua tau raug rau lub tshuab nqus tsev kom qhuav ntawm 80℃kom ntseeg tau tias cov khoom muaj dej noo raws li cov qauv xav tau. Cov crystals qhuav yog pulverized thiab granulated rau hauv 80-100 mesh hmoov, tom qab ntawd xa mus rau Lub Chaw Ntsuas Zoo rau kev soj ntsuam ntawm qhov tsis xws li cov khoom xyaw nquag, noo noo, hnyav hlau, thiab qib microbial. Thaum dhau kev soj ntsuam, cov khoom yog ntim raws li tus qauv specifications los tsim qhov kawgCoptis extract hmoovkhoom.

coptis chinensis cag extract ntawm daim tawv nqaij

Raws li nws qhov zoo- txhais los tiv thaiv- cov txheej txheem inflammatory, Coptis extract (uas yog cov khoom tseem ceeb yog berberine hydrochloride) kuj tau pom muaj txiaj ntsig tseem ceeb hauv kev noj qab haus huv ntawm daim tawv nqaij.. Cov kev tshawb fawb qhia tau hais tias berberine tuaj yeem cuam tshuam qhov zais cia ntawm pro- mob cytokines (xws li IL-6) thiab txo qis kev qhia ntawm COX-2 thiab iNOS los ntawm kev hloov pauv ntau txoj hauv kev, suav nrog NF-κB, MAPKs, thiab JAK-STAT.

 

Hauv kev kho pob txuv, nws inhibits proliferation ntawm Propionibacterium acnes, txo sebum secretion, thiab alleviates o ntawm daim tawv nqaij lesions. Tsis tas li ntawd, nyob rau hauv cov qauv simulating atopic dermatitis thiab psoriasis, nws pab kho cov tawv nqaij lipid barrier, inhibits lub hyperproliferation ntawm keratinocytes, thiab ameliorates inflammatory teb. Cov kev tshawb fawb no muab lub hauv paus kev tshawb fawb rau kev sivCoptis extracthauv kev tswj cov kab mob ntawm daim tawv nqaij xws li pob txuv, atopic dermatitis, thiab psoriasis.

coptis chinensis mob ntshav qab zib

Kev tshawb fawb qhia tau hais tias active cov khoom muaj nyob rau hauvCoptis extract-xws li berberine thiab coptisine- tuav tus nqi tshwj xeeb hauv kev cuam tshuam ntawm kev mob ntshav qab zib. Cov kev tshawb fawb tau lees paub tiasCoptis inflorescence extract tuaj yeem txhim kho pulmonary muaj nuj nqi thiab alleviate pathological kev puas tsuaj rau lub ntsws cov ntaub so ntswg hauv cov nas mob ntshav qab zib., thaum tib lub sijhawm nce HDL-C qib thiab txo qis TG, TC, thiab LDL-C.

 

Kev tshawb nrhiav kev siv tshuab tau nthuav tawm tias nws cov ntsiab lus tseem ceeb hauv lub cev -berberine thiab linarin- tau zoo inhibit siab - qabzib -induced alveolar epithelial- rau- hloov mesenchymal (EMT) los ntawm kev hloov kho lub AMPK / txoj kev raug mob. Qhov kev tshawb pom no muab lub hauv paus tshiab tshawb fawb los txo cov teeb meem ntshav qab zib los ntawm ob lub tswv yim ntawm kev txo cov ntshav qabzib thiab tswj cov kab mob lipid metabolic.

 

Siv:https://www.sciencedirect.com/science/article/abs/pii/S0378874113004972

https://www.sciencedirect.com/science/article/abs/pii/S0944711323003240

Kev siv tshuaj kho mob ntawm Coptis chinensis

Berberine hydrochloridetau dav siv rau hauv cov tshuaj kho mob xws li raws plab thiab ntshav qab zib; Tsis tas li ntawd, nws cov ntawv thov tau maj mam nthuav mus rau hauv thaj chaw ntawm cov kab mob plawv thiab paj hlwb, kev kho mob qog noj ntshav, thiab kev tiv thaiv kab mob.

Coptis chinensis ntxiv

Leveraging nws tej yam ntuj tso rau txo cov ntshav qab zib thiab lipids, nrog rau nws tiv thaiv kab mob -modulating teebmeem,Coptis chinensis extract hmoovtau tshwm sim los ua cov khoom tseem ceeb hauv ntau cov khoom noj khoom haus uas pab txhawb kev noj qab haus huv metabolic, yog li muab lub hauv paus txhim khu kev qha rau kev txhim kho cov khoom noj tshiab.

Pub Additives thiab Veterinary Medicines

Ntxiv mus, ua tsaug rau nws cov khoom tshwj xeeb antimicrobial,berberine hydrochloride hmoovtau dav siv los ua lwm txoj hauv kev rau cov tshuaj tua kab mob nyob rau hauv cov chaw ntawm cov tsiaj pub additives thiab veterinary tshuaj, yog li ua rau muaj txiaj ntsig zoo rau kev tswj hwm tsiaj noj qab haus huv.

Yog tias koj tab tom nrhiav siab - zooBerberine Hydrochloridecov ntaub ntawv raw, Kintai yog koj tus khub ntseeg siab. Raws li cov chaw tsim khoom ntawm Berberine nrog kev paub dhau los hauv R&D thiab kev tsim khoom, peb tshwj xeeb hauv kev muab cov nroj tsuag ntsuab rho tawm - feem ntau hauv daim ntawv ntawmCoptis chinensis cag extract hmoov. Peb cov khoom lag luam tseem ceeb tsom mus rau qhovCoptis chinensis Berberine: xyuasseries, featuring ibBerberine Hydrochloride hmoov khoommuab tau los ntawm Coptis chinensis nrog rau qib purity ncav cuag99%, nrog rau thib peb -cov ntaub ntawv tshaj tawm txog kev txheeb xyuas cov ntaub ntawv tsis huv thiab kev tshuaj xyuas cov ntsiab lus.

KINTAIBIO^®tuav ntau daim ntawv pov thawj- suav nrogGMP, ISO22000, HACCP, thiab HALAL-thiab tau nruab nrog lub teb chaws muaj ntawv pov thawj, cov qauv kuaj thiab cov kab ntau lawm. Peb muab kev pabcuam customization rau ntau yam khoom xyaw botanical, xws liCoptis extract hmoov, Coptis chinensis extract hmoov, thiab txheem suav qej extract. Ntau yam specifications-xws liCoptis chinensis cag extract hmoovntawm 10: 1 piv- tuaj yeem ua tau raws li qhov xav tau; Tsis tas li ntawd, peb muab cov khoom txhawb nqa ntsig txog Wolfberry extracts. Txawm hais tias koj xav tau cov khoom xyaw Coptis rau kev yuav khoom lossis xav tham txog kev txiav txim ntau ntawmCoptis chinensis cag extract, thov koj xav tiv tauj peb ntawmsales@kintaibio.com. Peb mob siab rau muab siab -zoo, zoo ib yamCoptis chinensis cag extract hmoovrau cov neeg siv khoom thoob ntiaj teb.

★ Yog tias koj xav tau siab - zooBerberine hydrochloride hmoov, thov koj xav tiv tauj peb ntawmsales@kintaibio.comlos yog tawm tswv yim nyob rau nplooj ntawv tom ntej.

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