Taxifolin, tseem hu ua dihydroquercetin, yog lub ntuj flavonoid compound uas tau txais kev saib xyuas hauv kev noj qab haus huv thiab kev noj qab haus huv kev lag luam. Qhov ntau yam phytochemical no tau ua raws li kev tshawb fawb dav dav vim nws cov txiaj ntsig kev noj qab haus huv, suav nrog antioxidant, tiv thaiv kab mob, thiab tshuaj tiv thaiv kab mob. Raws li kev txaus siab rau tej yam ntuj tso, cov nroj tsuag-raws li kev daws teeb meem rau kev noj qab haus huv thiab kev noj qab haus huv tseem loj hlob, kev nkag siab txog cov peev txheej thiab kev rho tawm ntawm taxifolin tau dhau los ua qhov tseem ceeb.
Lub hom phiaj ntawm tsab xov xwm no yog txhawm rau tshawb nrhiav cov peev txheej ntuj ntawm taxifolin, cov txheej txheem rho tawm siv kom tau txais nws, thiab cov pov thawj tshawb fawb txhawb nqa nws cov ntawv thov kev noj qab haus huv. Los ntawm delving rau hauv lub hauv paus chiv keeb thiab cov khoom ntawm no zoo kawg li compound, cov neeg nyeem yuav nkag siab tob txog nws lub peev xwm los pab rau tag nrho cov kev noj qab haus huv thiab kev noj qab nyob zoo.
Nkag siab Taxifolin
Taxifolin, tseem hu ua dihydroquercetin, yog ib qho flavonoid compound teej tug mus rau flavanone subclass. Nws cov qauv tshuaj muaj xws li ob lub nplhaib benzene txuas los ntawm tus choj peb-carbon, nrog ib pawg dihydroxyl ntawm ib lub nplhaib. Cov qauv tshwj xeeb no pab txhawb rau taxifolin lub zog antioxidant thiab bioactive zog (Shi li al., 2016).
Taxifolin muaj nyob rau hauv ntau yam nroj tsuag thiab zaub mov, nrog rau cov tawv ntoo, koob, thiab ntoo ntawm tej yam ntoo, thiab nyob rau hauv tej txiv hmab txiv ntoo thiab zaub. Cov peev txheej ntuj no ntawm taxifolin tau ua kom pom tseeb ntawm kev tshawb fawb dav, vim lawv tuav tus yuam sij rau kev qhib lub peev xwm kho mob ntawm qhov sib xyaw zoo kawg no.
Qhov chaw ntawm Taxifolin
Lub hauv paus ntuj tsim ntawm taxifolin yog cov tawv ntoo, koob, thiab ntoo ntawm qee hom ntoo, tshwj xeeb tshaj yog Siberian larch (Larix sibirica) thiab Douglas fir (Pseudotsuga menziesii) (Rogozhin & Pakhomov, 2013; Jain et al., 2020). Cov ntoo no paub tias khaws cov taxifolin hauv qhov ntau, ua rau lawv siv ntau tshaj plaws rau kev lag luam rho tawm.
Kev rho tawm ntawm taxifolin los ntawm cov peev txheej ntuj no feem ntau cuam tshuam nrog ntau cov txheej txheem. Thawj kauj ruam yog kom tau txais cov khoom siv cog qoob loo, xws li cov tawv ntoo lossis ntoo, los ntawm kev coj ua kom muaj txiaj ntsig zoo. Cov khoom cog yog ces raug rau cov kuab tshuaj extraction, feem ntau siv polar solvents xws li ethanol los yog methanol, xaiv extract cov taxifolin tebchaw (Rogozhin & Pakhomov, 2013). Cov txiaj ntsig extract tuaj yeem dhau mus ua cov kauj ruam ua kom huv ntxiv, xws li chromatography, kom cais cov ntshiabtaxifolincompound.
Cov txiaj ntsig kev noj qab haus huv thiab kev siv kho mob
Cov ntaub ntawv tshawb fawb tau ua tiav nrog cov kev tshawb fawb tshawb fawb txog ntau yam txiaj ntsig kev noj qab haus huv thiab kev siv tshuaj kho mob ntawm taxifolin. Cov kev tshawb fawb no tau nthuav tawm nws cov khoom muaj zog antioxidant thiab tiv thaiv kab mob, nrog rau nws lub peev xwm los cuam tshuam ntau yam ntawm tib neeg kev noj qab haus huv.
Antioxidant thiab Anti-inflammatory Properties
Taxifolin muaj npe nrov rau nws qhov tshwj xeeb antioxidant muaj peev xwm, uas yog vim nws cov qauv tshuaj lom neeg (Shi li al., 2016). Cov tshuaj flavonoid no muaj peev xwm tshem tawm cov dawb radicals, tshem tawm cov pa oxygen reactive, thiab txo oxidative kev nyuaj siab hauv lub cev. Tsis tas li ntawd, taxifolin tau pom tias yuav hloov kho txoj hauv kev inflammatory, txo cov kev tsim cov tshuaj tiv thaiv kab mob thiab txhawb kev daws teeb meem ntawm qhov mob (Rogozhin & Pakhomov, 2013).
Cov tshuaj antioxidant thiab cov tshuaj tiv thaiv kab mob ntawm taxifolin muaj qhov cuam tshuam loj rau kev noj qab haus huv thiab kev tiv thaiv kab mob. Los ntawm kev txo qis oxidative kev nyuaj siab thiab mob, taxifolin tuaj yeem ua lub luag haujlwm hauv kev tiv thaiv cov kab mob uas muaj hnub nyoog, xws li mob plawv, mob neurodegenerative, thiab qee yam mob qog noj ntshav (Shi li al., 2016).
Cov txiaj ntsig kho mob plawv
Ntau cov kev tshawb fawb tau tshawb xyuas cov txiaj ntsig zoo ntawm cov hlab plawv98% Taxifolin. Kev tshawb fawb tau pom tias taxifolin tuaj yeem txhim kho endothelial muaj nuj nqi, txhim kho cov hlab ntsha dilation, thiab txo cov roj cholesterol (Rogozhin & Pakhomov, 2013). Tsis tas li ntawd, taxifolin tau pom tias inhibit qhov tsim ntawm atherosclerotic plaques thiab txo qhov kev pheej hmoo ntawm thrombosis, yog li ua rau muaj kev noj qab haus huv ntawm cov hlab plawv (Shi li al., 2016).
Cov kev tshawb pom no qhia tias kev sib xyaw cov khoom noj uas nplua nuj taxifolin lossis tshuaj ntxiv rau hauv ib qho kev noj zaub mov tuaj yeem pab txhawb kev mob plawv, muaj peev xwm txo tau cov kab mob plawv, mob stroke, thiab lwm yam mob.
Neuroprotective Effects thiab Kev Paub Txog Kev Txawj Ntse
Cov ntaub ntawv pov thawj tshiab qhia tias taxifolin kuj tseem muaj cov khoom tiv thaiv neuroprotective thiab muaj peev xwm txhim kho kev txawj ntse. Cov kev tshawb fawb tau qhia tias taxifolin tuaj yeem tiv thaiv cov kab mob neurodegeneration, uas tuaj yeem ua rau qeeb qeeb ntawm cov mob xws li Alzheimer's thiab Parkinson's disease (Jain li al., 2020). Tsis tas li ntawd, taxifolin tau pom tias txhim kho kev nco, kev kawm, thiab kev paub tag nrho hauv kev tshawb fawb tsiaj thiab tib neeg (Rogozhin & Pakhomov, 2013).
Cov tshuaj tiv thaiv neuroprotective thiab kev txawj ntse-txhim kho cov teebmeem ntawm taxifolin tau xav tias yuav kho los ntawm nws cov tshuaj tiv thaiv antioxidant thiab tiv thaiv kab mob, nrog rau nws lub peev xwm los hloov kho cov kev taw qhia txoj hauv kev koom nrog hauv kev ua haujlwm neural thiab plasticity (Jain li al., 2020). Cov kev tshawb pom no qhia txog lub peev xwm ntawm taxifolin raws li kev cuam tshuam ntuj tsim los txhawb lub hlwb kev noj qab haus huv thiab kev txawj ntse.
Xaus
Taxifolin, ntau yam flavonoid compound, tau txais kev saib xyuas zoo rau nws cov txiaj ntsig kev noj qab haus huv thiab ntau yam kev siv. Lub hauv paus ntuj tsim ntawm taxifolin yog cov tawv ntoo, koob, thiab ntoo ntawm qee hom ntoo, tshwj xeeb tshaj yog Siberian larch thiab Douglas fir. Kev rho tawm ntawm taxifolin los ntawm cov peev txheej no feem ntau suav nrog kev tshem tawm cov kuab tshuaj thiab cov txheej txheem purification.
Cov ntaub ntawv pov thawj tshawb fawb tau ua pov thawj pom tias muaj zog antioxidant thiab tiv thaiv kab mob ntawm taxifolin, uas muaj feem cuam tshuam rau ntau yam ntawm tib neeg kev noj qab haus huv. Taxifolin tau pom tias pab txhawb kev mob plawv, tiv thaiv neurodegeneration, thiab muaj peev xwm txhim kho kev txawj ntse. Cov kev tshawb pom no qhia tias kev sib xyaw cov khoom noj uas nplua nuj taxifolin lossis tshuaj ntxiv rau hauv ib qho kev noj haus yuav ua rau muaj kev noj qab haus huv tag nrho thiab tiv thaiv kab mob.
Raws li kev tshawb fawb ntawm taxifolin txuas ntxiv nthuav dav, kev tshawb nrhiav ntxiv rau nws cov peev xwm kho mob thiab cov txheej txheem ntawm kev ua haujlwm yuav yog qhov tseem ceeb hauv kev qhib nws cov txiaj ntsig kev noj qab haus huv tag nrho. Cov neeg siv khoom thiab cov kws kho mob ib yam nkaus yuav tsum xav txog lub cev loj hlob ntawm cov pov thawj txhawb nqa kev siv taxifolin raws li ntuj tsim, cov tshuaj cog qoob loo los txhawb kev noj qab haus huv thiab kev noj qab haus huv.
PebTaxifolin Dihydroquercetin Bulk Powdertau txais kev qhuas zoo los ntawm cov neeg siv khoom. Yog tias koj xav paub ntau ntxiv txog cov khoom no, thov hu rau dawbSales@Kintaibio.Com.
Cov ntaub ntawv
Jain, A., Sharma, P., & Sharma, V. (2020). Dihydroquercetin (Taxifolin): Kev Tshawb Fawb Txog Kev Tshaj Tawm, Bioavailability, Pharmacokinetics thiab Pharmacological Activity. Tsob Ntoo Archives, 20(1), 1483-1489.
Rogozhin, VV, & Pakhomov, VP (2013). Dihydroquercetin: Lub Ntuj Antioxidant. Chemistry thiab Computational Simulation. Butlerov Communications, 33(1), 1-12.
Shi, GJ, Li, Y., Cao, QH, Wu, HX, Tang, XY, Gao, XH, ... & Yu, JQ (2016). Hauv vitro thiab hauv vivo pov thawj tias cov tshuaj tiv thaiv antioxidant ntawm Quercetin yog kho los ntawm kev tswj hwm ntawm arginase kev ua haujlwm hauv cov kab mob ntsig txog mob. Biochemistry thiab Biophysics Reports, 6, 105-113.
