Xi'an Kintai Biotech Inc yog ib qho ntawm cov tuam txhab kev paub ntau tshaj plaws thiab cov chaw muag khoom ntawm vine tshuaj yej extract hauv Suav teb. Thov koj xav tias dawb rau cov lag luam wholesale zoo vine tshuaj yej extract rau muag ntawm no los ntawm peb lub hoobkas. Rau nqe kev sab laj, tiv tauj peb.
Vine Tea Extract Chaw tsim tshuaj paus / tsum
KINTAIBIO®'s Vine tshuaj yej extracttuaj ntawm Tuam Tshoj sab qab teb. Nws yog lub npe hu ua "tus huab tais ntawm flavonoids" hauv Suav tshuaj yej kab lis kev cai. Peb tshem tawm cov active ingredientVine Tea Extract Dihydromyricetin (DHM)los ntawm nws cov tub ntxhais hluas stems thiab nplooj los ntawm niaj hnub refining technology. Cov khoom xyaw nquag no muaj ntau yam cuam tshuam rau kev tiv thaiv daim siab, txo cov ntshav lipids thiab ntshav qab zib, tiv thaiv - mob, tshuaj tua kab mob thiab antioxidant. Raws li ib tug natural ingredient,Dihydromyricetin hmoovkev nyab xeeb tau raug pov thawj thiab nws yog dav siv los ua raw khoom rau cov khoom tu tawv nqaij, khoom kho mob thiab tshuaj.
Cov ntaub ntawv hauv qab no muaj, thov hu rau peb ntawmsales@kintaibio.com.
* Specification
*Certificate of Analysis (CoA)
* Cov Ntaub Ntawv Kev Nyab Xeeb Cov Ntaub Ntawv (MSDS)
* Manufacturing process flow chart
* Daim Ntawv Qhia Txog Kev Tshawb Fawb Txog Kev Ua Haujlwm Siab Ua Kua Dej Chromatography (HPLC).
* Cov ntaub ntawv cuam tshuam ecological
* Cov impurities
* Cov ntaub ntawv ua tau zoo thib peb -toj xeem daim ntawv tshaj tawm
*Solvent residue thib peb -toj xeem tsab ntawv ceeb toom
* Cov ntsiab lus ntawm cov hlau hnyav thib peb -toj xeem daim ntawv tshaj tawm
*Aflatoxin thib peb-toj xeem tsab ntawv ceeb toom
* Daim ntawv qhia txog kev ua kom dej solubility
Vine Tea Extract specifcation & dihydromyricetin solubility
Siab -cov ntsiab lus 98% Vine tshuaj yej extract
Cov ntsiab lus siab -Vine tshuaj yej extractpeb tsim siv tshuab purification siab heev los rho tawm siab -puritydihydromyricetin extractlos ntawm cov tub ntxhais hluas stems thiab nplooj ntawm Ampelopsis grossedentata, kom ntseeg tau tias impurities raug tswj tsis pub dhau 0.5%. Tsis tas li ntawd, piv nrog cov tshuaj yej rattan tshuaj yej extracts, cov khoom no ua rau kom cov concentration ntawm DHM, ua rau txhua milligram nplua nuj nyob rau hauv cov tshuaj muaj zog tshuaj.
30% dej-soluble Vine tshuaj yej extract
Txawm tiasDHM Dihydromyricetinmuaj cov tshuaj pharmacological nplua nuj, nws tsis yooj yim soluble hauv dej thiab muaj qhov nqus tsawg hauv tib neeg lub cev, uas txwv tsis pub bioavailability ntawm cov khoom. Txhawm rau daws qhov teeb meem no, peb tsim 30% dej-solublecustomized dihydromyricetin hmoov. Los ntawm encapsulating DHM molecular qauv, siv sodium caseinate thiab -cyclodextrin, peb tau txhim kho nws cov solubility hauv dej, ua rau koj daim ntawv thov ntau dua. Tam sim no, qhov kev qhia tshwj xeeb no tau siv hauv kev saib xyuas tus kheej, cov khoom tu tawv nqaij thiab cov khoom noj thiab dej haus.
75% Vine tshuaj yej extract: Kev txhim kho bioavailability
Cov tsoos bioavailability ntawmVine tshuaj yej extracttsuas yog 4.21%, uas txhais tau hais tias feem ntau ntawm DHM noj tsis zoo absorbed thiab siv los ntawm tib neeg lub cev. Txhawm rau daws qhov teeb meem no, peb tau tsim kho tshiab DHM nrog rau bioavailability txog li 50%. Qhov kev siv thev naus laus zis no txhim khu kev ruaj ntseg thiab absorbability ntawmDHM Dihydromyricetin hmoovlos ntawm kev hloov kho molecularly, ua rau nws khaws cia ntev dua hauv cov hnyuv, yog li txhim kho qhov nqus tau zoo ntawm DHM los ntawm tib neeg lub cev.
Hauv no 75% DHM khoom,vine tshuaj yej extract dihydromyricetinTsis tsuas yog ua tiav qhov zoo tshaj plaws leap hauv bioavailability, tab sis tseem khaws tag nrho nws cov haujlwm qub. Txawm hais tias nyob rau hauv cov zaub mov noj qab haus huv, dej haus ua haujlwm, lossis cov khoom siv tshuaj, nws tuaj yeem ua tiav cov txiaj ntsig kev noj qab haus huv zoo dua nrog kev noj tsawg dua.
Lub cev thiab tshuaj muaj zog ntawm peb Vine Tea Extract dihydromyricetin
KINTAIBIO®siab -purityVine Tea Extractyog cov hmoov dawb uas tsis muaj solubility ntawm chav tsev kub thiab hauv dej txias. Nws yooj yim soluble hauv dej kub, kub ethanol, methanol, thiab me ntsis soluble hauv ethyl acetate. Vim tias nws muaj o-triphenolic hydroxyl qauv, nws yooj yim oxidized thiab muaj kev ruaj ntseg tsis zoo. Ntau yam xws li pH tus nqi, qhov kub thiab txias, hlau ions, thiab cov kuab tshuaj muaj kev cuam tshuam rau nws qhov ruaj khov.
Raws li peb lub tuam txhab kev tshawb fawb uas twb muaj lawm,tus nqi pHyog ib qho tseem ceeb cuam tshuam rau nws stability.DihydromyricetinNws ruaj khov nyob rau hauv qhov tsis muaj zog acidic nrog tus nqi pH tsawg dua lossis sib npaug li 4, tab sis qhov nce ntawm tus nqi pH yuav ua kom nws cov oxidation. Nyob rau hauv cov xwm txheej alkaline nrog tus nqi pH ntau dua lossis sib npaug li 9, nws yuav raug oxidized thiab tig daj. Qhov thib ob yam yogkub. Raws li qhov kub thiab txias, nws qhov tsis ruaj khov yuav nce ntxiv, thiab cov tshuaj tiv thaiv oxidation tsis tuaj yeem tshwm sim. Nws muaj qhov sib txawv rhiab heev rausib txawv hlau ions. Al3+, Fe3+, Cu2+, thiab lwm yam. ua si lub luag haujlwm catalytic hauv nws cov oxidation, thiab kev tiv tauj yuav tsum zam thaum siv.
COA ntawm Vine Tea Extract
Dab tsi yog Vine Tea Extract Cov txiaj ntsig?
Vine Tea Extract dihydromyricetin rau mob qog noj ntshav
DHM tau nthuav tawm ntau-txoj kev muaj peev xwm hauv kev cuam tshuam qog noj ntshav.Cov kev tshawb fawb tau pom tias DHM tuaj yeem cuam tshuam kev loj hlob ntawm ntau yam qog noj ntshav, suav nrog mob ntsws cancer, mob qog nqaij hlav, thiab mob qog noj ntshav ntawm lub mis, los ntawm inhibiting qog angiogenesis, inhibiting cell proliferation, inducing apoptosis, thiab inhibiting cancer cell invasion and migration. Nyob rau theem molecular,Vine Tea Extract DHMtuaj yeem tswj hwm txoj hauv kev tseem ceeb ntawm mammalian signaling pathways thiab inhibit lub epithelial -mesenchymal hloov (EMT) txheej txheem, yog li cuam tshuam nrog malignant evolution ntawm cov qog ntawm ntau theem.
Ib txhij,DHM Dihydromyricetinmuaj cov kev tswj xyuas bidirectional rau autophagy, nthuav tawm cov teebmeem sib txawv hauv ntau hom mob qog noj ntshav. Qhov tseem ceeb, thaum DHM tau siv ua ke nrog kev kho mob tshuaj tiv thaiv kab mob xws li doxorubicin thiab nedaplatin, nws tuaj yeem txhim kho kev ua tau zoo thiab rov qab cov tshuaj tiv thaiv qog noj ntshav, ua kom pom qhov zoo ntawm kev kho tus nqi.
Vine Tea Extract dihydromyricetin rau daim tawv nqaij
DHM, raws li RAGE inhibitor, tuaj yeem ncua kev laus ntawm daim tawv nqaij.Cov kev tshawb fawb tau pom tias DHM tuaj yeem txo qis D-galactose- ua rau cov tsos mob ntawm daim tawv nqaij laus hauv cov nas, txhim kho daim tawv nqaij elasticity thiab tswj cov ntsiab lus collagen, thaum txhawb kev loj hlob ntawm daim tawv nqaij. Hauv kev sim hauv vitro,DHM hmoovKev kho mob tau nce lub peev xwm loj hlob ntawm senescent fibroblasts induced los ntawm advanced glycation kawg cov khoom (AGEs) los ntawm kwv yees li 1.5 npaug thiab txo qhov kev qhia ntawm ntau yam kev laus -txog biomarkers.
Lub core molecular mechanism nyob rau hauvVine Tea ExtractLub peev xwm los txo qis qhov kev qhia ntawm AGER gene encoding RAGE receptor thiab, nrog rau nws txoj kev sib koom siab siab, khi ncaj qha rau RAGE, yog li kev sib tw inhibiting AGE-RAGE teeb liab txoj hauv kev thiab nws cov kev cuam tshuam qis qis, thaum ib txhij upregulating cov kev qhia ntawm cov noob muaj feem xyuam rau lub voj voog ntawm tes thiab DNA kho.
Vine Tea Extract rau Antioxidant Activity
Cov kws tshawb fawb cuam tshuam los ntawm peb pab neeg tau pom tias pebVine Tea Extractmuaj peev xwm tseem ceeb antioxidant. Ntawm lawv, kev sim kuaj pom tau tiasKINTAIBIO®dihydromyricetin muaj qhov khawb ntawm 73.3% mus rau 91.5% ntawm ruaj khov dawb radicals DPPH, thiab tuaj yeem cuam tshuam linoleic acid peroxidation ntawm qhov concentration ntawm 0.01% mus rau 0.04%. Nws cov nyhuv zoo ib yam li cov hluavtaws antioxidants. Oxidant TBHQ yog piv los yog zoo dua. Nws cov txheej txheem antioxidant hauv linoleic acid peroxidation system tshwm sim los ntawm FeSO4 yog ua rau Fe²⁺ complex, yog li tiv thaiv cov tshuaj tiv thaiv peroxidation tshwm sim los ntawm Fe²⁺.
Tsis tas li ntawd, nws tuaj yeem tiv thaiv lipoxygenase zoo, nrog ib nrab inhibitory concentration (EC50) ntawm 6.7 txog 74.1 mmol, qhia kev sib tw inhibition ntawm linoleic acid ntawm qhov chaw nquag ntawm lipoxygenase. Nws muaj zog scavenging nyhuv ntawm dawb radicals O2⁻, ROO⁻ thiab OH⁻. Nws lub peev xwm scavenging rau DPPH dawb radicals muaj zog dua vitamin C (Vc), thiab nws ua rau kom muaj zog SOD (superoxide dismutase). , txo cov MDA (malondialdehyde) cov ntsiab lus.
Vine Tea Extract rau Antibacterial kev ua haujlwm
KINTAIBIO®'s vine tshuaj yej extractdihydromyricetin muaj dav -spectrum antibacterial teebmeem rau ntau yam Gram-positive thiab Gram-cov kab mob tsis zoo, xws li Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, thiab Fu Shigella, Bacillus subtilis, Salumrabesiellaphine, Kleumrabesiella, b txhua tus tau pom muaj qhov cuam tshuam rau cov kab mob tseem ceeb, thiab qhov tsawg kawg nkaus inhibitory concentration (MIC) tsawg.
Vine Tea Extract rau Anti-inflammatory thiab tiv thaiv- ua xua
KINTAIBIO®cov kws tshawb fawb pom tiasVine Tea Extract dihydromyricetinmuaj cov tshuaj tiv thaiv - mob thiab tiv thaiv - ua xua. Nws inhibits qhov dilation thiab nce permeability ntawm cov hlab ntsha auricular nyob rau hauv ib koob tshuaj - nyob ntawm seb, txo qhov℃ntawm edema, thiab qhia tau hais tias muaj zog npaum li cas. Inhibitory nyhuv rau mob o. Nws cov tshuaj tiv thaiv - mob thiab tiv thaiv - kev ua xua feem ntau inhibits kev tsim cov leukotrienes, metabolite ntawm arachidonic acid, inhibits synthesis lossis tso tawm ntawm histamine, thiab tshem tawm cov pa dawb radicals.
Vine Tea Extract rau Inhibition ntawm tyrosinase kev ua haujlwm
Cov kws tshawb fawb pom tias cov khoom xyaw no muaj qhov cuam tshuam loj heev rau cov monophenolase thiab diphenolase ntawm tyrosinase, nrog rau inhibition ntawm 95.87% thiab 69.01% raws li.Vine Tea ExtractDMY inhibits monophenolase los ntawm kev ncua lub sij hawm lag luam ntawm enzyme - catalyzed cov tshuaj tiv thaiv (los ntawm 0.38 feeb mus rau 0.97 feeb), thiab inhibition ntawm diphenolase qhia tau hais tias ib tug reversible mix inhibition hom, qhia tias dihydromyricetin yog ib tug natural tyrosinase Inhibitors.
Tau qhov twg los: https://www.mdpi.com/2072-6694/14/14/3487
https://www.mdpi.com/2072-6643/17/11/1862
Dab tsi yog Vine Tea Extract siv?
Raws li kev sim tshuaj pharmacological tshiab,Vine tshuaj yej extractmuaj cov teebmeem hauv qab no rau kev noj qab haus huv:
1) Antioxidant
2) Anticancer thiab tiv thaiv -cov nyhuv qog
3) Kev tiv thaiv daim siab thiab lub raum
4) Hypolipidemic thiab hypotensive teebmeem
5) Txhim kho thiab tswj kev tiv thaiv kab mob
6) Tiv thaiv - inflammatory thiab bacteriostatic teebmeem
7) Antithrombotic nyhuv
Diversified thov kev cia siab
Nrog peb txoj kev vam meej hauvVine tshuaj yej extractKev siv tshuab thev naus laus zis, cov khoom siv siab -DHM cov khoom siv tsis yog tsuas yog siv los ua cov khoom xyaw tseem ceeb ntawm cov khoom noj qab haus huv thiab khoom noj khoom haus, tab sis kuj tseem tuaj yeem siv dav hauv kev saib xyuas tus kheej, pub additives, kev cog qoob loo cog qoob loo thiab lwm thaj chaw. Los ntawm kev txhim kho tag nrho cov nqi sib txawv ntawm rattan tshuaj yej extracts, peb muab cov kev daws teeb meem ruaj khov thiab noj qab nyob zoo rau ntau yam lag luam.
★ Yog tias koj xav tau siab - zooVine Tea Extract, thov koj xav tiv tauj peb ntawmsales@kintaibio.comlos yogtawm tswv yim nyob rau nplooj ntawv tom ntej.
Cim npe nrov: Suav teb vine tshuaj yej extract manufacturers, lwm tus neeg, Hoobkas
